Generic

Ocular Irrigating Solution (Calcium Chloride + Magnesium Chloride + Potassium Chloride + Sodium Chloride + Sodium Acetate + Sodium Citrate)

Q: What is this solution used for?

It is used as an extraocular and intraocular irrigating solution during ocular surgical procedures (< 60 minutes).

Q: How is it used?

It should be used according to the standard format for each surgical procedure.

Q: What are the side effects?

Corneal swelling, bullous keratopathy, corneal clouding, post-operative inflammatory reactions may occur.

Q: Who should not use this solution?

Patients with allergy to any of the ingredients should not use it.

Q: What should I check before using the solution?

Ensure the solution is clear, seal is intact, vacuum is present, container is undamaged, and there is no discoloration or precipitate.

3 brands available in the market

At a glance

Ocular Irrigating Solution (Calcium Chloride + Magnesium Chloride + Potassium Chloride + Sodium Chloride + Sodium Acetate + Sodium Citrate) is a sterile solution used as an extraocular and intraocular irrigating solution during various ocular surgical procedures involving perfusion of the eye with an expected maximum duration of less than 60 minutes.

Description

Ocular Irrigating Solution is a sterile solution used for extraocular and intraocular irrigation during various ocular surgical procedures involving perfusion of the eye with an expected maximum duration of less than 60 minutes. The solution contains Calcium Chloride, Magnesium Chloride, Potassium Chloride, Sodium Chloride, Sodium Acetate, and Sodium Citrate.

Calcium Chloride prevents and treats negative calcium balance and facilitates nerve and muscle function. Potassium Chloride is a major cation of intracellular fluid, playing a role in nerve impulse conduction. Sodium Chloride is the major extracellular cation important for electrolyte and fluid balance. Sodium Acetate serves as an alternate source of bicarbonate by metabolic conversion in the liver. Sodium Citrate alkalinizes urine and binds with urinary calcium.

Indications

Extraocular and intraocular irrigation during ocular surgical procedures (< 60 minutes)

Therapeutic class

Ophthalmic Irrigating Solution

Pharmacological class

Intraocular Irrigating Solution

Pharmacology

Calcium Chloride prevents or treats negative calcium balance and regulates action potential excitation threshold to facilitate nerve and muscle performance. Potassium Chloride is a major cation of intracellular fluid, playing an active role in nerve impulse conduction and muscle contraction. Sodium Chloride is the major extracellular cation important for electrolyte and fluid balance. Sodium Acetate is an alternate source of bicarbonate by metabolic conversion in the liver. Sodium Citrate alkalinizes urine and binds with urinary calcium.

Mechanism of action

This solution is used for irrigating the intraocular and extraocular surfaces during surgery, maintaining electrolyte balance and keeping tissues hydrated.

Dosage

Adults and Children: This irrigating solution should be used according to the standard format for each surgical procedure.

Note: Expected maximum duration is less than 60 minutes.

Administration

For use as an irrigating solution during ocular surgery only. Not for injection or intravenous infusion. Administered by healthcare professionals during surgery.

Missed dose

Hospital-only medicine. Administered by doctor or surgeon during surgery. Missed dose concept does not apply (part of the surgical procedure).

Side effects

Ocular-related: Corneal swelling (corneal edema), bullous keratopathy, corneal clouding, corneal decompensation, post-operative inflammatory reactions.

Irrigation or any other trauma may result in corneal swelling or bullous keratopathy.

Precautions & warnings

Use with caution in diabetic patients (especially during vitrectomy) as intraoperative lens changes have been observed.
Not for injection or intravenous infusion.
Do not use unless the product is clear, seal is intact, vacuum is present, and container is undamaged.
Do not use if the product is discolored or contains a precipitate.

Contraindications

Known hypersensitivity to any of the ingredients

Drug interactions

No significant drug interactions are known.

Food interactions

No food-related restrictions (surgical irrigation).

Use in pregnancy

Adequate information on use during pregnancy is not available; consult your doctor.

Use in lactation

Adequate information on use during lactation is not available; consult your doctor.

Pediatric use

Use in children according to the standard format for each surgical procedure.

Geriatric use

No specific dose adjustment required for elderly.

Renal / hepatic impairment

Renal impairment: Systemic absorption is minimal; however, consult your doctor.

Hepatic impairment: Systemic absorption is minimal; however, consult your doctor.

Overdose effects

Overuse may cause corneal edema, bullous keratopathy, or other corneal complications. Consult your doctor if symptoms occur.

Storage conditions

Store below 30°C, away from light. Keep out of reach of children.

Chemical structure

Calcium Chloride + Magnesium Chloride + Potassium Chloride + Sodium Chloride + Sodium Acetate + Sodium Citrate

Common questions

What is this solution used for?

It is used as an extraocular and intraocular irrigating solution during ocular surgical procedures (< 60 minutes).

How is it used?

It should be used according to the standard format for each surgical procedure.

What are the side effects?

Corneal swelling, bullous keratopathy, corneal clouding, post-operative inflammatory reactions may occur.

Who should not use this solution?

Patients with allergy to any of the ingredients should not use it.

What should I check before using the solution?

Ensure the solution is clear, seal is intact, vacuum is present, container is undamaged, and there is no discoloration or precipitate.

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.