Generic
Riboflavin
13 brands available in the market
At a glance
Riboflavin (Vitamin B2) is used for prevention and treatment of riboflavin deficiency conditions such as cheilosis, angular stomatitis, glossitis, keratitis, seborrheic dermatitis, and microcytic anemia.
Description
Riboflavin is an easily absorbed, water-soluble micronutrient that supports energy production by aiding in the metabolism of fats, carbohydrates, and proteins. It is required for red blood cell formation and respiration, antibody production, and regulating human growth and reproduction. It is essential for healthy skin, nails, hair growth, and thyroid activity.
Indications
- Riboflavin deficiency (cheilosis, angular stomatitis, glossitis, keratitis, seborrheic dermatitis)
- Microcytic anemia
- Migraine prevention
- Cataract prevention
Therapeutic class
Vitamin-B preparations
Pharmacological class
Vitamin B2 (Riboflavin)
Pharmacology
Riboflavin functions as a coenzyme in the metabolism of fats, carbohydrates, and proteins. It is a precursor of FMN and FAD. Its antioxidant activity is derived from its role as a precursor of FAD, which is required for the production of reduced glutathione for glutathione peroxidases.
Mechanism of action
Acts as a coenzyme in energy metabolism and antioxidant defense.
Dosage
Adult Dose (Oral):
- Riboflavin deficiency: 5-30 mg/day in divided doses
- Migraine prevention: 400 mg/day (up to 3 months for best results)
- Cataract prevention: approximately 2.6 mg/day
Pediatric Dose (Oral):
- Riboflavin deficiency (3-12 years): 3-10 mg/day in divided doses
- (>12 years): 5-30 mg/day in divided doses
Administration
- Take with food
- Take at the same time each day
Missed dose
If you miss a dose, take it as soon as you remember; skip if it's almost time for next dose; do not double the dose.
Side effects
Side Effects:
- Bright yellow discoloration of urine
- High doses: Diarrhea, increased urine output
Precautions & warnings
- Caution with doses above RDA during pregnancy
- Non-toxic; no warnings or precautions established
Contraindications
- Hypersensitivity to riboflavin
Drug interactions
- Propantheline bromide: Rate and extent of absorption may be affected
- Anticholinergic drugs, tricyclic antidepressants, phenobarbital, probenecid
Food interactions
Not food-related; alcohol consumption is safe.
Use in pregnancy
Use in Pregnancy: Safe for pregnant women at recommended amounts; caution with doses above RDA.
Use in lactation
Use in Lactation: Safe for breastfeeding women at recommended amounts.
Pediatric use
Pediatric dose based on age; consult your doctor.
Geriatric use
Caution required in elderly patients; consult your doctor.
Renal / hepatic impairment
Renal Impairment: Caution in kidney disease; consult your doctor.
Hepatic Impairment: Caution in liver disease; consult your doctor.
Overdose effects
No overdose information available; consult your doctor if taken in excess.
Storage conditions
Store in a cool and dry place, protected from light.
Chemical structure
Riboflavin