Generic
Triamcinolone Acetonide Mouth prep
4 brands available in the market
At a glance
Triamcinolone Acetonide Mouth prep is a steroid used for mouth ulceration. It provides relief by reducing inflammation.
Description
Triamcinolone has mainly glucocorticoid activity. It suppresses the migration of polymorphonuclear leukocytes and reduces capillary permeability, thereby decreasing inflammation.
Indications
- Mouth ulceration
Therapeutic class
Corticosteroid, Glucocorticoids
Pharmacological class
Corticosteroid
Pharmacology
Triamcinolone has mainly glucocorticoid activity. It suppresses the migration of polymorphonuclear leukocytes and reduces capillary permeability, thereby decreasing inflammation.
Mechanism of action
Blocks production of chemical messengers that cause inflammation, reducing inflammation.
Dosage
Adult Dose (Mouth/Throat):
- Mouth ulceration: A small amount (about 0.6 cm) of the 0.1% paste is pressed onto the lesion without rubbing until a thin film develops. Apply 2 or 3 times daily, preferably after meals. Re-evaluate if recovery does not occur after 7 days of treatment.
Administration
- For mouth use only
- Do not rub; press onto lesion
- Apply after meals
Missed dose
If you miss a dose, apply it as soon as you remember; if almost time for next dose, skip it; do not double the dose.
Side effects
Common Side Effects:
- Local burning
- Itching
- Irritation
- GI upsets
- Increased fragility of mucosa of the mouth
Precautions & warnings
- Caution in diabetes, hypertension, renal and liver impairment, glaucoma, psychosis, delayed tissue healing, cirrhosis, heart failure, recent MI, hypothyroidism, osteoporosis, peptic ulceration, thromboembolic disorders
- Monitor height in children on prolonged therapy
- Avoid rapid drug withdrawal
Contraindications
- Untreated systemic fungal, bacterial, viral or parasitic infection
- Hypersensitivity
Drug interactions
- Lowering of plasma salicylates levels
- NSAIDs: increased risk of GI bleeding and ulceration
- Antidiabetics: antagonised blood glucose-lowering effects
- Amphotericin B, beta agonists, beta-blockers, potassium-depleting diuretics, theophylline: increased risk of hyperkalaemia
- Ciclosporin, carbamazepine, phenytoin, barbiturate, rifampicin: increased clearance of triamcinolone
- Live vaccines: infections may develop
Food interactions
Food interactions are not significant.
Use in pregnancy
Use in Pregnancy: Caution needed; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Caution needed; consult your doctor.
Pediatric use
Caution in elderly, children, pregnancy, lactation
Geriatric use
Caution required in elderly patients
Renal / hepatic impairment
Renal Impairment: Caution needed; consult your doctor
Hepatic Impairment: Caution needed; consult your doctor
Overdose effects
Symptoms: Adrenal suppression.
Treatment: Supportive care.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.