Generic
Undenatured Type-II Collagen + Hyaluronic Acid + Methylsulfonylmethane + Turmeric + Boswellia serrata
2 brands available in the market
At a glance
Undenatured Type-II Collagen + Hyaluronic Acid + Methylsulfonylmethane + Turmeric + Boswellia serrata is indicated for osteoarthritis, rheumatoid arthritis, joint pain & inflammation, difficulties in flexibility & mobility, and joint discomfort & stiffness (knee extension).
Description
Undenatured Type II Collagen is derived from chicken sternum cartilage preserving the triple helix. Hyaluronic acid binds water, providing lubrication and shock absorption. MSM has anti-inflammatory and antioxidant effects. Turmeric extract contains curcumin. Boswellia serrata inhibits 5-LOX.
Indications
- Osteoarthritis
- Rheumatoid arthritis
- Joint pain & inflammation
- Difficulties in flexibility & mobility
- Joint discomfort & stiffness (knee extension)
Pharmacological class
Herbal and Nutraceuticals
Pharmacology
Undenatured Type II Collagen is derived from chicken sternum cartilage using a patented, low-temperature, non-enzymatic process. Hyaluronic acid binds water, providing lubrication and shock absorption. MSM has anti-inflammatory and antioxidant effects. Turmeric extract contains curcumin. Boswellia serrata inhibits 5-LOX.
Mechanism of action
Undenatured collagen II epitopes trigger oral tolerization, releasing collagen-specific regulatory T-cells. Hyaluronic acid provides lubrication and shock absorption. MSM has anti-inflammatory and antioxidant effects. Curcumin inhibits pro-inflammatory signals. Boswellic acid inhibits 5-LOX.
Dosage
Adult Dose (Oral):
- 1 capsule twice daily with meal or as directed by the physician
Administration
- Take with meal
- Take as directed by a physician
Missed dose
If you miss a dose, take it as soon as you remember; if almost time for next dose, skip it; do not double the dose.
Drug interactions
No known interactions.
Food interactions
Food interactions are not significant.
Contraindications
- Hypersensitivity to Undenatured Type-II Collagen, Hyaluronic Acid, MSM, Turmeric Extract or Boswellia serrata Extract
Side effects
Common Side Effects:
- Well tolerated at recommended dose
- Side effects are rare; some may feel stomach problems
Use in pregnancy
Use in Pregnancy: No studies have evaluated use during pregnancy; take with caution and medical advice.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: No studies have evaluated use during lactation; take with caution and medical advice.
Precautions & warnings
- Contraindicated in patients with known hypersensitivity to Undenatured Type-II Collagen, Hyaluronic Acid, MSM, Turmeric Extract or Boswellia serrata Extract
- Safety and effectiveness under 18 years not established
Pediatric use
Safety and effectiveness under 18 years not established
Geriatric use
Safe for elderly
Renal / hepatic impairment
Renal Impairment: Limited information
Hepatic Impairment: Limited information
Overdose effects
Symptoms: Stomach problems.
Treatment: Supportive care.
Therapeutic class
Drugs for Osteoarthritis, Herbal and Nutraceuticals, Specific mineral preparations
Storage conditions
Store in a cool & dry place below 30°C, protected from direct sunlight & moisture. Keep out of reach of children.