Generic
Undenatured Type-II Collagen + Hyaluronic Acid + Methylsulfonylmethane + Turmeric + Boswellia serrata
2 brands available in the market
At a glance
Undenatured Type-II Collagen + Hyaluronic Acid + Methylsulfonylmethane + Turmeric + Boswellia serrata is indicated for osteoarthritis, rheumatoid arthritis, joint pain & inflammation, difficulties in flexibility & mobility, and joint discomfort & stiffness (knee extension).
Description
Undenatured Type II Collagen is derived from chicken sternum cartilage preserving the triple helix. Hyaluronic acid binds water, providing lubrication and shock absorption. MSM has anti-inflammatory and antioxidant effects. Turmeric extract contains curcumin. Boswellia serrata inhibits 5-LOX.
Indications
- Osteoarthritis
- Rheumatoid arthritis
- Joint pain & inflammation
- Difficulties in flexibility & mobility
- Joint discomfort & stiffness (knee extension)
Therapeutic class
Drugs for Osteoarthritis, Herbal and Nutraceuticals, Specific mineral preparations
Pharmacological class
Herbal and Nutraceuticals
Pharmacology
Undenatured Type II Collagen is derived from chicken sternum cartilage using a patented, low-temperature, non-enzymatic process. Hyaluronic acid binds water, providing lubrication and shock absorption. MSM has anti-inflammatory and antioxidant effects. Turmeric extract contains curcumin. Boswellia serrata inhibits 5-LOX.
Mechanism of action
Undenatured collagen II epitopes trigger oral tolerization, releasing collagen-specific regulatory T-cells. Hyaluronic acid provides lubrication and shock absorption. MSM has anti-inflammatory and antioxidant effects. Curcumin inhibits pro-inflammatory signals. Boswellic acid inhibits 5-LOX.
Dosage
Adult Dose (Oral):
- 1 capsule twice daily with meal or as directed by the physician
Administration
- Take with meal
- Take as directed by a physician
Missed dose
If you miss a dose, take it as soon as you remember; if almost time for next dose, skip it; do not double the dose.
Side effects
Common Side Effects:
- Well tolerated at recommended dose
- Side effects are rare; some may feel stomach problems
Precautions & warnings
- Contraindicated in patients with known hypersensitivity to Undenatured Type-II Collagen, Hyaluronic Acid, MSM, Turmeric Extract or Boswellia serrata Extract
- Safety and effectiveness under 18 years not established
Contraindications
- Hypersensitivity to Undenatured Type-II Collagen, Hyaluronic Acid, MSM, Turmeric Extract or Boswellia serrata Extract
Drug interactions
No known interactions.
Food interactions
Food interactions are not significant.
Use in pregnancy
Use in Pregnancy: No studies have evaluated use during pregnancy; take with caution and medical advice.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: No studies have evaluated use during lactation; take with caution and medical advice.
Pediatric use
Safety and effectiveness under 18 years not established
Geriatric use
Safe for elderly
Renal / hepatic impairment
Renal Impairment: Limited information
Hepatic Impairment: Limited information
Overdose effects
Symptoms: Stomach problems.
Treatment: Supportive care.
Storage conditions
Store in a cool & dry place below 30°C, protected from direct sunlight & moisture. Keep out of reach of children.