Aclitol Cozycap

Maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD).

Aclidinium bromide is a long-acting anticholinergic that inhibits M3 receptors causing smooth muscle relaxation. Formoterol fumarate is a selective long-acting beta2-agonist that increases cAMP levels leading to bronchial relaxation.

400 mcg/12 mcg twice daily (one inhalation capsule in the morning and one in the evening) via an inhalation device.

Common adverse effects include upper respiratory tract infection and headache. Tremor, palpitations, dry mouth, or urinary retention may occur.

No adequate and well-controlled studies in pregnant women. Use only if potential benefit justifies potential risk.

Pregnancy Category: Respiratory Safety Precaution — always consult a doctor before taking during pregnancy.

Not for acute bronchospasm or acute COPD exacerbations. Use with caution in convulsive disorders, thyrotoxicosis, diabetes, narrow-angle glaucoma, or prostatic hyperplasia.

Overdosage may produce exaggerated beta-agonist/anticholinergic effects such as tachycardia, tremor, dry mouth, or cardiac arrhythmias. Provide supportive care.

Store below 25°C in a dry place. Protect from light and moisture. Keep out of reach of children.