Acliz PLUS
25mg+50mgRx৳ 3.50/unit
Pack: ৳ 35
৳ 3.50/unit
Pack: ৳ 35
At a glance
Meclizine Hydrochloride + Pyridoxine Hydrochloride is a combination medicine used for vertigo and motion sickness. It prevents nausea, vomiting, light-headedness, and other symptoms of vertigo.
Indications
- Vertigo
- Motion sickness
- Prevention and treatment of nausea and vomiting
- Radiation sickness
Pharmacology
Meclizine reduces labyrinthine apparatus sensitivity to block vomiting signals; Pyridoxine enhances anti-emetic effects and acts as a dietary supplement.
Dosage
Adults and Children 12 years+:
- Motion sickness: 25-50 mg (meclizine), 1 hour before travel; repeat every 24 hours if needed
- Vertigo: 25-100 mg daily in divided doses
- Radiation sickness: 50 mg, 2-12 hours prior to radiation treatment
- Pyridoxine: 50-200 mg/day
Side effects
Common Side Effects:
- Dry mouth
- Allergic reaction
- Drowsiness
- Headache
- Fatigue
- Blurred vision (rare)
Use in pregnancy
Use in Pregnancy: Meclizine + Pyridoxine is generally considered safe during pregnancy (Category B); large-scale human studies have not demonstrated adverse fetal effects; it is the drug of first choice for nausea and vomiting during pregnancy.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution when driving or doing activities requiring concentration (may cause drowsiness and dizziness)
- Avoid alcohol (may cause excessive drowsiness)
- Do not use with other sedating medications (cough and cold medicines)
- Caution in asthma, glaucoma, or prostate enlargement
- Consult doctor during pregnancy and lactation
Overdose effects
Overdose may cause extreme excitability, seizures, drowsiness, and hallucinations; supportive and symptomatic treatment; consider dialysis.
Storage conditions
Store below 30°C, away from light and moisture; keep out of reach of children.