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At a glance

Saffron (Crocus sativus) is a natural supplement used as a mood enhancer and antidepressant. It is effective in major depressive disorder, dysthymia, premenstrual, postpartum, and postmenopausal depression, PTSD, fibromyalgia, cognitive impairment, and Alzheimer's disease.

Indications
  • Major depressive disorder
  • Dysthymia
  • Premenstrual depression
  • Postpartum depression
  • Postmenopausal depression
  • Post-traumatic stress disorder (PTSD)
  • Fibromyalgia
  • Cognitive impairment
  • Alzheimer's disease
Pharmacology

Saffron exhibits antidepressant effects by increasing dopamine, norepinephrine, and serotonin levels in the hippocampus. It switches off chronic inflammation in the hippocampus and increases neural plasticity to form new neural connections. Its antioxidant and neuroprotective properties also make it effective in Alzheimer's disease.

Dosage

Dosage:

  • 1-2 capsules daily after meals (morning or night)
  • Treatment duration: Minimum 4 weeks
  • Repeat course as advised by the physician
Side effects

Side Effects:

  • Well tolerated at recommended doses; no serious adverse effects reported
  • Rare cases of mild headache or stomach discomfort
Use in pregnancy

Use in Pregnancy: Not recommended during pregnancy; consult your doctor.

Pregnancy Category: B — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution in patients taking anticoagulant or antiplatelet drugs (may inhibit platelet aggregation)
  • Caution in bleeding disorders
  • Do not use in children under 12 years
Overdose effects

No overdose information available; consult your doctor if overused.

Storage conditions

Store below 30°C, protected from light and moisture; keep out of reach of children.

Saffron — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.