Aggreno25mg+200mg
Rx- Generic:
- Aspirin + Dipyridamole
- Company:
- Ziska Pharmaceuticals Ltd.
- Dosage form:
- Capsule
- Pack size:
- Strip (10 Capsule)
৳ 12/unit
Pack: ৳ 120
At a glance
Aspirin + Dipyridamole — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Aspirin + Dipyridamole is a combination of two medicines that mainly prevent clot formation in the blood vessels. It also helps to prevent another stroke in patients with a history of previous stroke or mini-stroke (transient ischaemic attack). Aspirin + Dipyridamole should be taken with food regularly at a fixed time each day. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. Lifestyle changes like low-fat diet, exercise and not smoking may help this medicine to work better. Diarrhea, indigestion, and vomiting are some common side effects of this medicine. This medicine increases your risk of bleeding, so it is important to be careful while shaving, cutting nails and using sharp objects. Usually, it is advisable to avoid alcohol intake while taking this medicine. Before taking this medicine, tell your doctor if you have any liver or kidney disease. You must tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Aspirin + Dipyridamole is a combination of two antiplatelet medicines: Aspirin and Dipyridamole which prevent stroke following an initial first stroke (transient ischaemic attack). It works by preventing platelets from sticking together which decreases the formation of harmful blood clots.
Indications
• Blood clots
Mechanism of action
Aspirin inhibits platelet aggregation by irreversible inhibition of platelet cyclooxygenase and thus the formation of thromboxane A2 in the platelets. Dipyridamole inhibits platelet aggregation by preventing the uptake of adenosine into platelets, endothelial cells and RBCs. The combination results in additive antiplatelet effects.
Dosage
Adult Dose: Stroke Secondary prophylaxis of transient ischemic attack (TIA) or cerebrovascular accident (CVA) Adult: 1 capsule bid Hepatic impairment: Avoid in severe impairment. Renal Dose: Renal impairment: CrCl (ml/min) <10: Avoid.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aspirin + Dipyridamole is to be taken with food.
Side effects
Common: • Increased bleeding tendency • Diarrhea • Indigestion • Vomiting • Headache
Precautions & warnings
[UNSAFE] Aspirin + Dipyridamole may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Arreno Capsule ER for preventing blood clots that cause a stroke. It can be taken with or without food. Arreno Capsule ER increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling). Notify your doctor if you experience stomach pain, nausea or vomiting that doesn't go away. Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
Contraindications
Hypersensitivity, allergy to NSAIDs. Bleeding disorders (factor VII or IX deficiencies). Patients with asthma, rhinitis or nasal polyps. Children <16 yr with viral infections.
Drug interactions
Aspirin: May reduce hypotensive and hyponatraemic effects of ACE inhibitors; may increase serum levels and toxicity of acetazolamide; increases anticoagulant effect of heparin, thus increasing bleeding risk; may reduce hypotensive effect of β-blockers; may reduce efficacy of diuretics in patients with underlying renal or CV disease; salicylate may inhibit renal clearance of methotrexate, thus increasing the risk of bone marrow toxicity; increased risk of bleeding or reduced renal function when used with NSAIDs; increased risk of hypoglycaemia when used with oral hypoglycaemic drugs; salicylate antagonises the uricosuric effect of uricosuric agents; may increase adverse effect of alendronate. Dipyridamole: May antagonise the anticholinesterase effect of cholinesterase inhibitors. Increased risk of bleeding when used with warfarin. Antiplatelet effect of aspirin may be increased by antidepressants e.g. TCAs, selective serotonin reuptake inhibitors. Potentially Fatal: Salicylates may increase adverse effect of drotrecogin alfa. Dypyridamole may increase plasma levels and CV effects of adenosine. Ketorolac may enhance adverse effect of aspirin. Dipyridamole may increase therapeutic effect of regadenoson. Salicylates may increase the anticoagulant effect of vit K antagonists. Salicylates may increase the adverse effect of varicella virus-containing vaccines.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Aspirin + Dipyridamole.
Use in pregnancy
[CONSULT YOUR DOCTOR] Aspirin + Dipyridamole is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Aspirin + Dipyridamole is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Aspirin + Dipyridamole is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Aspirin + Dipyridamole may not be needed in these patients. Please consult your doctor. [SAFE IF PRESCRIBED] Aspirin + Dipyridamole is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Aspirin + Dipyridamole may not be needed in these patients. Please consult your doctor.
Common questions
My father in law is being admitted in hospital due to blood clot in brain. His right leg and arm seems to be paralysed. Doctors in the hospital not briefing us on the problem exactly. Need your second opinion. His age is 67. Having Smoking habit. There are blood clots in the brain arteries I am TIA patient taking ARRENO and statin (20mg) for last 3 years as clopidogrel did not suit me. Recently i developed leg pain especially after long walk and while sleeping. Colour doppler indicated Astheroclerotic wall calcification in anterior and posterior tibial arteries of lower limbs. Since i am already taking arreno, doctor did not advise me any medicine and only when pain increases over a period of time i can think of. Recently i developed little more (still i can walk without pain for 3 km a day normal walk). I got done CT angio which indicated both anterior and posterior of both legs are severely hypoplastic. The vascular specialist suggested me to take Stiloz 50mg along with Arreno. I seek advise whether i can take both these medicines that have identical in terms of mechanism of work. Will i have any problem if i take Stiloz along with Arreno ? Kindly advise. Stiloz has different action U can take it along side In 3 months pregnancy some blood clots have came Get an USG done urgently I had high blood pressure on 10 jan 2017 and on 12 jan2017 i had blood clot making discomfort in my nose and i have thyroid too am taking pills for it plz tell me why m having these blood clots in my nose consult ENT surgeon, how can i tell without looking or examininng I was pregnant in January. I was feeling all symptoms of being pregnant. When I was undergone SCG test, It was negative. Even my blood report also shows absence of HCG. As I am feeling pregnancy symptoms, I continued to do HCG tests for 3 .5months. During this tenure, I had almost no monthly periods.(only sometimes spots seen). I consulted Gynaecologist for this problems. I had undergone sonography test two times. It was showing some blood clots. Doctor suggested to do Anti Mullerian hormone test for uneven/ stopped period for long time. He also gave tablets for period which was consumed by me and I had period for four days in first week of April. AMH test showed worrying result. It was showing value- 0.7. A lower normal range is 0.7 to .0.9. Doctor suggested to complete three month course of OVARUS (75mg) tables. Is there any worries about lower AMH ? What is the reason for this problem? I have thyroid problem and I am taking Eltroxine 100mg since last 7 years. Yes low amh shows poor ovarian reserve and it indicates that u should try for pregnancy soon My father had a stroke and minor blood clots has been noticed in mri so is there any cure of it in auurveda Yes, Cap Ksheera bala twice a day one morning and one night and tab Dhanvantari Vati 1-0-1 and Syp CardoriumPlus 15 ml twice a day after food for 3 monthsPhysiotherapy also will help She is my mother. She is having blood clots in legs as well as arms. These clot does not give any pain. But these also don't vanishes. Please provide me some information what can I do to remove these. She also have blood pressure problem. Please provide remedy for that too. She is afraid of going to doctor. That's why I am asking here. Hope, I will get useful response Thank u Hi kindly need to consult face to face so once consult to your nearest doctor