Akicin 500
Rx- Generic:
- Amikacin
- Company:
- Square Pharmaceuticals PLC.
- Dosage form:
- Injection
- Pack size:
- Box (10 Injection)
৳ 48.14/unit
Pack: ৳ 481.40
Price comparison
- This brand
- ৳ 48.14
- Cheapest of this genericMikacin
- ৳ 45
The cheaper brand costs ৳ 3.14 less per unit
Compared against 7 brands
At a glance
Amikacin is an aminoglycoside antibiotic used for serious Gram-negative bacterial infections. It is effective in septicemia, respiratory tract infections, bone and joint infections, meningitis, skin infections and urinary tract infections.
Indications
Bacterial septicemia (including neonatal sepsis); serious respiratory tract infections; bone and joint infections; CNS infections (including meningitis); skin and soft tissue infections; intra-abdominal infections (including peritonitis); burns and postoperative infections; complicated and recurrent UTIs; gentamicin and tobramycin-resistant infections; staphylococcal infections.
Dosage
Adults and children: 15 mg/kg/day in two equally divided doses (equivalent to 500 mg twice daily in adults).
Neonates and premature children: Initial loading dose 10 mg/kg, then 15 mg/kg/day in two equally divided doses.
Life-threatening or Pseudomonas infections: 500 mg every 8 hours (max 1.5 g/day, max total 15 g).
UTIs (non-pseudomonal): 7.5 mg/kg/day in two equally divided doses (250 mg twice daily in adults).
Renal impairment: Reduce dose or increase dosing interval.
Side effects
Common side effects: Increased blood urea, injection site reactions, nausea, vomiting, skin rash, drug fever, headache, paresthesia.
Serious (rare): Hearing loss (tinnitus, vertigo, partial or complete reversible/irreversible deafness), kidney damage, balance disorder, ototoxicity, nephrotoxicity.
Precautions & warnings
- Concurrent use with myorelaxants may cause respiratory arrest
- Avoid combination with other aminoglycosides (increased ototoxicity and nephrotoxicity)
- Increased ototoxicity risk with fast-acting diuretics (in renal failure)
- Increased nephrotoxicity with cephalosporins or polymyxins
- Do not use during pregnancy (fetal ototoxicity risk)
- Ensure adequate hydration during treatment (to minimize kidney damage)