Alodia 25
Rx- Generic:
- Alogliptin
- Company:
- The ACME Laboratories Ltd.
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
৳ 22/unit
Pack: ৳ 220
At a glance
Alogliptin is a DPP-4 inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in type-2 diabetes mellitus.
Description
Alogliptin slows incretin hormone inactivation, increasing bloodstream concentrations to reduce fasting and postprandial glucose in type 2 diabetes.
Indications
Adjunct to diet and exercise to improve glycaemic control in adults with type-2 diabetes mellitus.
Therapeutic class
Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Pharmacological class
Antidiabetic Agent
Pharmacology
Inhibits DPP-4 enzyme, slowing incretin hormone degradation, enhancing insulin secretion and reducing glucagon levels.
Mechanism of action
DPP-4 inhibition leading to increased active GLP-1 and GIP levels.
Dosage
25 mg once daily for normal or mild renal impairment; dose adjustments required for moderate to severe renal impairment.
Administration
Oral administration with or without food.
Missed dose
Take as soon as remembered.
Side effects
Nasopharyngitis, headache, upper respiratory tract infection.
Precautions & warnings
Acute pancreatitis, hypersensitivity reactions, hepatic effects.
Contraindications
History of serious hypersensitivity reaction to Alogliptin-containing products.
Drug interactions
Negligible CYP-related metabolism; no significant drug-drug interactions.
Food interactions
No significant food interactions.
Use in pregnancy
Pregnancy Category B. Use only if clearly needed.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Use in lactation
Exercise caution when administered to a nursing woman.
Pediatric use
Safety and effectiveness not established in pediatric patients.
Geriatric use
No overall differences observed in safety or effectiveness compared to younger patients.
Renal / hepatic impairment
Dose adjustment needed for moderate to severe renal impairment; use caution in severe hepatic impairment.
Overdose effects
Supportive therapy and clinical monitoring as dictated by clinical status.
Storage conditions
Keep below 30°C, away from light & moisture. Keep out of reach of children.
Chemical structure
Small molecule DPP-4 inhibitor
Common questions
Question: What is Alogliptin used for? Answer: It is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type-2 diabetes mellitus. Question: What is the standard dosage of Alogliptin? Answer: 25 mg once daily in patients with normal or mild renal impairment, with dose adjustments for moderate to severe renal impairment. Question: Can it be used during pregnancy? Answer: It should be used during pregnancy only if clearly needed (Pregnancy Category B).