Andep 50
Rx- Generic:
- Sertraline Hydrochloride
- Company:
- Healthcare Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
৳ 5.50/unit
Pack: ৳ 55
At a glance
Sertraline Hydrochloride — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Sertraline Hydrochloride is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is prescribed for depression and anxiety-related conditions like panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder (PTSD). Sertraline Hydrochloride is also used to treat premenstrual dysphoric disorder (depression and irritability before menstrual period in women). It can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc). To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks. Some common side effects of Sertraline Hydrochloride include nausea, indigestion, loss of appetite, increased sweating, tremors, insomnia (difficulty in sleeping), and diarrhea. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself. Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe. Sertraline Hydrochloride is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of post traumatic stress disorder, obsessive-compulsive disorder, panic disorder, premenstrual dysphoric disorder and anxiety.
Indications
• Depression • Post traumatic stress disorder • Obsessive-compulsive disorder • Panic disorder • Premenstrual dysphoric disorder • Anxiety
Mechanism of action
Sertraline has a potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to sustained activity at the postsynaptic receptor sites and improvement of depression. Reduction of serotonin turnover (in brain) also contributes to its action. Its long half-life allows once daily admin.
Dosage
Adult Dose: Oral Major Depressive Disorder; Obsessive compulsive disorder Adult: Initially, 50 mg daily, may increase in increments of 50 mg at wkly intervals. Max: 200 mg daily. Panic disorder with or without agoraphobia; Posttraumatic stress disorder; Social anxiety disorder Adult: Initially, 25 mg daily, increased to 50 mg daily after a wk. May increase in increments of 50 mg at wkly intervals. Max: 200 mg daily. Premenstrual dysphoric disorder Adult: Initially, 50 mg daily, either throughout the menstrual cycle or during the luteal phase only. May increase in increments of 50 mg per menstrual cycle. Max: 150 mg daily (for continuous dosing) or 100 mg daily (during luteal phase). Patient who require 100 mg daily during luteal phase-only: Initially, 50 mg daily for the first 3 days of each luteal phase period. Hepatic impairment: Reduce dose. Child Dose: Oral Obsessive compulsive disorder Child: 6-12 yr Initially, 25 mg once daily; 13-17 yr Initially, 50 mg once daily. May increase at intervals of at least 1 wk. Max: 200 mg daily. Renal Dose: Renal impairment: Dose adjustment not necessary
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sertraline Hydrochloride may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Sertraline Hydrochloride, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Delayed ejaculation • Erectile dysfunction • Indigestion • Insomnia (difficulty in sleeping) • Low sexual desire • Nausea • Tremor • Diarrhea • Increased sweating • Loss of appetite
Precautions & warnings
[UNSAFE] Sertraline Hydrochloride may cause side effects which could affect your ability to drive. Do not drive or do anything requiring concentration until you know how Sertraline Hydrochloride affects you. Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts. The addiction/dependence potential of Sertraline Hydrochloride is very less. Inform your doctor if you experience decreased sex drive or difficulty having an orgasm. Do not stop taking the medication suddenly without talking to your doctor.
Contraindications
Sertraline is contraindicated in patients with a known hypersensitivity to Sertraline or any of the excipients of drug. Concurrent use or w/in 14 days of discontinuation of MAOIs (e.g. linezolid or IV methylene blue). Concomitant use w/ pimozide.
Drug interactions
May increase risk of delirium when used with antimuscarinics. Increased risk of extrapyramidal symptoms and neuroleptic malignant syndrome when used with aripiprazole. Serum levels may be reduced by carbamazepine. Concurrent use with dihydroergotamine or linezolid may lead to serotonin syndrome. May increase serum levels of lamotrigine and risk of toxicity. May increase serum levels of olanzapine, pimozide, risperidone, methadone, clozapine and amiodarone. Plasma levels may be increased by cimetidine and ritonavir. May increase the anticoagulant activity of warfarin and acenocoumarol. Potentially Fatal: Concomitant admin with MAOIs can result in serious serotonin syndrome.
Food interactions
[UNSAFE] Sertraline Hydrochloride may cause excessive drowsiness with alcohol.
Use in pregnancy
[CONSULT YOUR DOCTOR] Sertraline Hydrochloride may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Sertraline Hydrochloride is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Sertraline Hydrochloride is safe to use in patients with kidney disease. No dose adjustment of Sertraline Hydrochloride is recommended. However, inform your doctor if you have an underlying kidney disease as you may be given a smaller dose initially and then increased slowly as required. [CAUTION] Sertraline Hydrochloride should be used with caution in patients with liver disease. Dose adjustment of Sertraline Hydrochloride may be needed. Please consult your doctor. Use of Sertraline Hydrochloride is not recommended in patients with severe liver disease.
Common questions
What is the best ayurvedic medicine for lethargy,dullness,obsessive compulsive disorder, bipolar mood disorder,general anxiety disorder,gas,bloating,low digestive strength,low body energy,low concentration,too much attachment and paranoid behavior? https://www.1mgayush.com/otc/jiva-ashwagandha-tablet-otc3299671-1 Tablet after lunch & dinner, Take at least 1-2 months. I have Obsessive compulsive Disorder. Prescribe the medication. Hi Kindly share your symptoms of your Problem how to tackle depression and post traumal stress disorder? Psychiatric evaluation is based on history, clinical symptoms, personality factors, ongoing psychosocial stressors and frequency and severity of symptoms. It requires direct interaction with the patient on a regular basis. Once diagnosed, a management plan is formed based on intensity and frequency of symptoms and associated biological and psycho social factors. A complete solution to ones problems in a single question is thus not possible. Internet will give you generalised tips and tricks but they are hardly of any use. I suggest you to visit a psychiatrist in your vicinity for clinical evaluation. PANIC ATTACK ANXIETY DISORDER T Anxiety is the result of a hyperarousal state of nervous system due to a low threshold for threat perception. In simpler words, it's an ongoing flight or fight response. It can elicit a neuro-hormonal response understood as Flight or Fright reaction kicking in physiological cascade of symptoms ranging from palpitations, tachycardia, breathlessness, increased bowel movement, increase frequency of urination, dizziness, muscle tension or pain, trembling, dizziness, blurring of vision to restlessness, confusion and fainting spells. Chronic stress causes prolonged anxiety response with the consequences of slowed me ration, lack of concentration, headaches, fluctuations in blood pressure and increased wear and tear of body tissues. Identifying your stressors, learning to deal with them, de stressing regularly by doing something that makes one feel good, yoga and meditation are some non pharmacological strategies to deal with it. If the condition is persisting for a long time, it's better to see a psychiatrist. Mental Depression , Anxiety disorder Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended. panic disorder, hypochondria syndrome & anxiety neurosis Continue medicines as prescribed and follow up with your psychiatrist Sir i am suffering from Anxiety, IBS and Obsessive compulsive disorder I want to how i get Ayurveda medicine You should contact Ayurvedic doctor in person before starting the treatment Please prescribed tab for Depression, Anxiety, Specifically Somatoform (pain) disorder. Tab SHOULD NOT cause Flatulance & Constipation as side-effects i.e. tabs other than opiprol, duvanta,serta please. Consult a Psychiatrist for this prescription. Secondly anxiety depression patient needs derailed assessment and dose titration as these medicines have a potential for addiction and may harm If taken in excess