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At a glance

Oxazepam is a benzodiazepine used for anxiety disorders and alcohol withdrawal symptoms. It enhances GABA's inhibitory effect to suppress abnormal and excessive activity of nerve cells in the brain.

Indications
  • Anxiety disorders (especially tension, irritability and agitation in elderly)
  • Acute alcohol withdrawal symptoms
Pharmacology

Oxazepam enhances GABA's inhibitory effect to suppress excessive nerve cell activity in the brain, reducing anxiety and agitation.

Dosage

Adult Dose (Oral):

  • Mild-moderate anxiety: 10-15 mg 3-4 times daily
  • Severe anxiety/agitation: 15-30 mg 3-4 times daily
  • Alcohol withdrawal: 15-30 mg 3-4 times daily
  • Insomnia (anxiety-related): 15-25 mg 1 hour before bedtime

Elderly Dose: 10 mg 3 times daily (initial); increase to 10-20 mg 3-4 times daily if needed

Pediatric Dose (>12 years): 10-15 mg 3-4 times daily (mild-moderate); 15-30 mg 3-4 times daily (severe)

Side effects

Common Side Effects:

  • Drowsiness
  • Dizziness
  • Nausea
  • Lethargy
  • Edema
  • Slurred speech
  • Tremor
  • Altered libido
  • Rash
Use in pregnancy

Use in Pregnancy: Oxazepam is highly unsafe during pregnancy; definite evidence of fetal harm.

Pregnancy Category: D — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • High addiction/habit-forming potential
  • Do not stop suddenly (withdrawal symptoms may occur)
  • Should not be used for more than 4 weeks
  • Caution while driving
  • Avoid alcohol
  • Elderly patients may have reduced muscle tone and increased risk of falls
Overdose effects

Overdose: Drowsiness, confusion, ataxia, coma, respiratory depression; flumazenil as antidote.

Storage conditions

Store in a cool and dry place, protected from light and moisture; keep out of reach of children.

Oxazepam — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.