Anspar200mg

Sparfloxacin is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues and lungs (pneumonia). It cures the infection by stopping the further growth of the causative microorganisms. Sparfloxacin should be used in the dose and duration as advised by your doctor. It may be taken with or without food, preferably at a fixed time of the day. Avoid taking antacids containing aluminum or magnesium within 2 hours before or 2 hours after you take this medicine, as this reduces the efficacy of this medicine. You should not skip any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned. You may have dizziness, stomach pain, nausea and bitter taste as side effects of this medicine. These are usually temporary and resolve on their own, but please consult your doctor if they bother you or persist for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools. You should not take this medicine if you are allergic to any of its ingredients. Rarely, some people may have a severe allergic reaction which needs urgent medical attention. Signs of this include rash, swelling of the lips, tongue or face, shortness of breath or breathing problems. Special care should be taken in people with kidney problems while taking this medicine. Sparfloxacin is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.

• Bacterial infections

Sparfloxacin inhibits the supercoiling activity of DNA gyrase which is an enzyme essential for DNA replication thus promoting the breakage of DNA structures. It has activity against S. pneumoniae, S. aureus, H. influenzae, K. pneumoniae, M. catarrhalis and Mycobacterium spp.

Adult Dose: Oral Adult 2 tablets (400 mg) on 1st day as a loading dose, followed by 1 tablet (200 mg) daily as a maintenance dose. Duration of maintenance treatment is 10 days. Renal Dose: Renal impairment (Creatinine clearance < 50 ml/min) is 2 tablets (400 mg) taken on the first day as a loading dose. Thereafter, 1 tablet of 200 mg should be taken every 48 hours for total 9 days of therapy.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sparfloxacin may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Sparfloxacin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Dizziness • Stomach pain • Nausea • Bitter taste • Indigestion • Diarrhea

[UNSAFE] Sparfloxacin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Your doctor has prescribed Sparfloxacin to cure your infection and improve symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Discontinue Sparfloxacin and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools. Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations. Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Hypersensitivity; pregnancy and lactation; children <18 yr.

Cations such as aluminum, magnesium, zinc and iron may reduce the bioavailability of sparfloxacin. May increase the plasma concentrations of theophylline and tizanidine. May enhance the effect of warfarin and glibenclamide. May decrease the renal clearance of methotrexate. Excretion may be reduced by probenecid. May alter serum levels of phenytoin. Potentially Fatal: Corticosteroids may increase risk of tendon rupture. Increased risk of seizures with NSAIDs. Risk of additive QT prolongation effect when used with class Ia or III antiarrhythmic drugs, astemizole, terfenadine, cisapride, erythromycin, pentamidine, phenothiazines or TCAs.

[SAFE] Consuming alcohol with Sparfloxacin does not cause any harmful side effects.

[CONSULT YOUR DOCTOR] Sparfloxacin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Sparfloxacin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Sparfloxacin may cause diarrhea or rash in the baby.

[CAUTION] Sparfloxacin should be used with caution in patients with kidney disease. Dose adjustment of Sparfloxacin may be needed. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Sparfloxacin in patients with liver disease. Please consult your doctor.

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