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At a glance

Snake Venom Antiserum is used for the treatment of snake bites. It neutralizes the harmful effects of snake venom. It is indicated for bites by Cobra, Common Krait, Russell's Viper, and Saw-Scaled Viper.

Indications
  • Bite by Cobra (Naja naja)
  • Bite by Common Krait (Bungarus caeruleus)
  • Bite by Russell's Viper (Vipera russelli)
  • Bite by Saw-Scaled Viper (Echis carinatus)
Pharmacology

Snake Venom Antiserum binds to snake venom components and neutralizes them. It contains F(ab')2 immunoglobulin fragments that bind to antigenic sites on snake venom, inhibiting their biological activity (neurotoxins, hemotoxins) and facilitating their elimination from the body.

Dosage

Initial Dose (IV Infusion):

  • Adults and children: 5-10 vials slow IV infusion (not more than 2 ml/min) or diluted in normal/glucose saline at 5-10 ml/kg body weight over 1 hour
  • Additional 5-10 vials if WBCT shows coagulopathy after 6 hours (hemotoxic) or symptoms persist after 1 hour (neurotoxic)
  • Total dose: 15-20 vials in most cases
Side effects

Side Effects:

  • Early or delayed allergic reactions (anaphylaxis)
  • Breathlessness
  • Decreased blood pressure
  • Joint pain
  • Serum sickness
  • Shock, hives
Use in pregnancy

Use in Pregnancy: Pregnancy is not a contraindication; use if needed; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution in known hypersensitivity to product constituents
  • Avoid IM injections in hemotoxic bites (until coagulopathy corrected)
  • Release tourniquets slowly after starting antivenom
  • Monitor vital signs frequently
Overdose effects

Overdose may increase risk of allergic reactions; provide symptomatic treatment.

Storage conditions

Lyophilized preparation is stable at room temperature; store in a cool and dark place; avoid excessive heat.

Snake Venom Antiserum — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.