Apetiz160mg

Megestrol Acetate is used to treat breast cancer and endometrial cancer. It specifically helps treat breast and endometrial cancer that are hormone dependent. It may also be used for treating low appetite and weight loss in patients with advanced cancer or HIV. Megestrol Acetate should be taken with or without food, preferably at a fixed time each day to ensure consistent levels of medicine in the body. This medicine is not used for pregnant or breastfeeding women. It may cause side effects like high blood pressure and increased blood sugar levels but they are temporary. However, if these persists, consult with the doctor. Megestrol Acetate is a progestin (female hormone). It works in patients with breast cancer and endometrial cancer by affecting female hormones involved in cancer growth. It causes weight gain by increasing appetite.

• Breast cancer • Endometrial cancer

Megestrol is a progestogen used as an antineplastic and appetite stimulant. The mechanism of it's antineoplastic effects is not known but may be due to inhibition of oestrogen synthesis, modulation of other steroid hormones and/or a direct cytotoxic effect on tumour cells.

Adult Dose: Oral Palliative treatment of breast carcinoma Adult: 40 mg 4 times daily or 160 mg once daily. Palliative treatment of endometrial carcinoma Adult: 40-320 mg daily in divided doses. evaluate efficacy after 2 months of treatment; up to 800 mg/day may be used Anorexia and cachexia in patients with cancer or AIDS Adult: Initial: 800 mg daily. Usual range: 400-800 mg daily. Renal Dose: Renal impairment: Use with caution; in normal renal function, 57-78% is excreted in urine within 10 days

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Megestrol Acetate may be taken with or without food, but it is better to take it at a fixed time.

Common: • Increased appetite • Weight gain • Hot flashes • High blood pressure • Constipation • Increased glucose level in blood

[SAFE] Megestrol Acetate does not usually affect your ability to drive. Megestrol Acetate is used to treat women with certain hormone-dependent cancers such as breast cancer and endometrial cancer. It may also be used for treating appetite and weight loss in people with advanced cancer or AIDS. You may have to take it for atleast 2 months before you notice any changes in your appetite. Your doctor might do regular blood tests to check your hormones and blood sugar levels while you are taking this medicine. Do not take Megestrol Acetate if you are pregnant or breastfeeding. Inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision. These could be symptoms of a blood clot in a vein. Do not stop taking the medicine suddenly without talking to your doctor first.

Pregnancy and lactation. Severe hepatic impairment.

Concentrations of indinavir may be reduced. Possible reduced efficacy of cisplatin. Warfarin half life may be increased. Megestrol concentration may be decreased by aminoglutethimide and enzyme-inducing drugs.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Megestrol Acetate. Please consult your doctor.

[UNSAFE] Megestrol Acetate is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

[CONSULT YOUR DOCTOR] Megestrol Acetate is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[CAUTION] Megestrol Acetate should be used with caution in patients with severe kidney disease. Dose adjustment of Megestrol Acetate may be needed. Please consult your doctor. [CAUTION] Megestrol Acetate should be used with caution in patients with severe liver disease. Dose adjustment of Megestrol Acetate may be needed. Please consult your doctor.

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