Aproxi Ezy125mg+80mg+80mg
Rx- Generic:
- Aprepitant
- Company:
- Beacon Pharmaceuticals PLC
- Dosage form:
- Capsule
- Pack size:
- Box (3 Capsule)
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৳ 116.66/unit
Pack: ৳ 349.98
At a glance
Aprepitant is an antiemetic medication used to prevent nausea and vomiting caused by chemotherapy and postoperative nausea and vomiting in adults.
Indications
- Prevention of chemotherapy-induced nausea and vomiting (CINV)
- Prevention of postoperative nausea and vomiting (PONV)
Dosage
Postoperative Nausea and Vomiting (PONV):
- 40 mg orally within 3 hours prior to induction of anesthesia
Chemotherapy-Induced Nausea and Vomiting (CINV):
Highly Emetogenic Chemotherapy:
| Day | Aprepitant | Dexamethasone | 5HT3 Antagonist |
|---|---|---|---|
| Day 1 | 125 mg (1 hr before chemo) | 12 mg (30 min before chemo) | Ondansetron 24 mg (30 min before chemo) |
| Day 2 | 80 mg (morning) | 8 mg (morning) | — |
| Day 3 | 80 mg (morning) | 8 mg (morning) | — |
| Day 4 | — | 8 mg (morning) | — |
Moderately Emetogenic Chemotherapy:
| Day | Aprepitant | Dexamethasone | 5HT3 Antagonist |
|---|---|---|---|
| Day 1 | 125 mg (1 hr before chemo) | 12 mg (30 min before chemo) | Ondansetron 8 mg (30 min before chemo) + 8 mg (8 hr later) |
| Day 2 | 80 mg (morning) | — | Ondansetron 8 mg twice daily |
| Day 3 | 80 mg (morning) | — | Ondansetron 8 mg twice daily |
Special Populations: No dose adjustment needed in renal impairment. No dose adjustment needed in mild-moderate hepatic impairment. No dose adjustment needed in elderly patients.
Side effects
- Headache
- Dizziness
- Hiccup
- Loss of appetite
- Fatigue
- Constipation
- Hypotension
- Pruritus
- Pyrexia
Precautions & warnings
Serious Precautions:
- Will not help if you already have nausea and vomiting
- Do not use continuously for a long time
- May damage sperms and may harm the baby if used during pregnancy or breastfeeding
- May cause dizziness and sleepiness - do not drive if affected
- May cause diarrhea - drink plenty of fluids
- Consult your doctor if pregnant, planning pregnancy or breastfeeding
- Inform your doctor if you have kidney or liver diseases
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.