Azactum1gm/vial
Rx- Generic:
- Aztreonam
- Company:
- Drug International Ltd.
- Dosage form:
- Injection
- Pack size:
- Injection
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৳ 400/unit
Pack: ৳ 400
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At a glance
Aztreonam is a monobactam beta-lactam antibiotic used to treat various infections caused by gram-negative bacteria. It works by inhibiting bacterial cell wall synthesis.
Indications
- Urinary tract infections (cystitis, pyelonephritis)
- Lower respiratory tract infections (pneumonia)
- Intra-abdominal infections (peritonitis)
- Skin and soft tissue infections
- Gynecological infections (pelvic inflammatory disease)
- Septicemia
- Bone and joint infections
- Meningitis
- Pseudomonas aeruginosa infections in cystic fibrosis
- Infections in penicillin-allergic patients
Dosage
Adults: 1-2 g every 8-12 hours; severe infections: 2 g IV every 8 hours.
Pediatrics: 30-50 mg/kg every 8 hours, not to exceed adult dose. Neonates and infants: careful dose adjustment needed.
Renal dose: CrCl 10-30 mL/min: 1-2 g loading dose, then 50% of usual dose; CrCl <10 mL/min: 1-2 g loading dose, then 25% of usual dose.
Side effects
- Rash
- Injection site reactions (pain, swelling, redness)
- Vomiting
- Nausea
- Diarrhea
- Cough
- Nasal congestion
- Wheezing
- Sore throat
- Pyrexia
- Chest discomfort
- Abdominal pain
Rare: Anaphylaxis, angioedema, bronchospasm, pancytopenia, neutropenia, thrombocytopenia
Precautions & warnings
- Discontinue immediately if hypersensitivity reactions (anaphylaxis, angioedema) occur
- Prolonged use may lead to superinfection
- Caution in patients with allergy to penicillin or other beta-lactams
- Caution during pregnancy and lactation
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.