Barbipan30mg
Rx- Generic:
- Phenobarbitone (Phenobarbital)
- Company:
- Albion Laboratories Ltd.
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 1/unit
Pack: ৳ 1
At a glance
Phenobarbitone (Phenobarbital) — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Phenobarbitone (Phenobarbital) belongs to a class of medicines called barbiturates. It is a prescription medicine used to treat and prevent epilepsy (seizures). They also have hypnotic properties. Means, they slow down the activity of the brain and can make you feel sleepy or dizzy. Phenobarbitone (Phenobarbital) may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it may be habit-forming with long-term use. If you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. Some common side effects of this medicine include nausea, diarrhea, hyperactivity, depression, confusion, decreased blood pressure and fatigue. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Remember to consult your doctor if you notice severe rashes, especially accompanied by fever after taking this medicine. It should be noted that long-term use of this medicine can cause pain in joints also. Phenobarbitone (Phenobarbital) controls seizures or fits by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.
Indications
• Epilepsy/Seizures
Mechanism of action
Phenobarbitone is a short-acting barbiturate. It depresses the sensory cortex, reduces motor activity, changes cerebellar function, and produces drowsiness, sedation and hypnosis. Its anticonvulsant property is exhibited at high doses.
Dosage
Adult Dose: Oral Sedation Adult: 30-120 mg daily in 2-3 divided doses, do not exceed 400 mg/day Status epilepticus ; Emergency management of acute seizures Adult: 100-300 mg daily at bedtime. Generalised tonic-clonic seizures, Partial seizures Adult: 60-180 mg/day at night. Insomnia Adult: 100-200 mg daily at bedtime, do not exceed 400 mg/day As a hypnotic Adult: 100-320 mg. Do not admin for >2 wk for the treatment of insomnia. Elderly: Reduce dose. Hepatic impairment: Reduce dose. Severe: Contraindicated. Child Dose: Oral Sedation Child: 2 mg/kg daily in 3 divided doses. Status epilepticus ; Emergency management of acute seizures Child: 3-5 mg/kg or 125 mg/m2 daily. Seizures Neonates (12 years: 1-3 mg/kg/day in 1-2 divided doses, OR 50-100 mg BID/TID Preoperative sedation Child: 1-3 mg/kg pre-op. Renal Dose: Renal impairment: Reduce dose. Severe: Contraindicated.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Phenobarbitone (Phenobarbital) may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Drowsiness • Nausea • Diarrhea • Hyperactivity • Depression • Confusion • Decreased blood pressure • Fatigue • Headache • Dizziness • Constipation • Excitement • Hangover
Precautions & warnings
[UNSAFE] Phenobarbitone (Phenobarbital) may cause side effects which could affect your ability to drive. Phenobarbitone (Phenobarbital) helps in treatment and prevention of seizures. It may be habit-forming with long-term use. Talk with your doctor if it stops working well. Do not take more than prescribed. It may make you very sleepy. Don't drive or do anything that requires mental focus until you know how it affects you. Inform your doctor if you notice pain in your joints or if you have a history of bone disease. Get regular blood tests done to monitor the amount of medication in your body. Talk to your doctor immediately if you notice skin rash accompanied with fever. Do not stop taking the medication suddenly without talking to your doctor.
Contraindications
Severe renal and hepatic disorders. Severe respiratory depression, dyspnoea or airway obstruction; porphyria. Pregnancy.
Drug interactions
May enhance the hepatotoxic potential of paracetemaol overdoses. May decrease levels/effects of various CYP isoenzyme substrates e.g. teniposide, methotrexate, antipsychotics, beta-blockers, calcium-channel blockers, other anticonvulsants, chloramphenicol, cimetidine, corticosteroids, ciclosporin, doxycycline, oestrogens, felbamate, griseofulvin, tacrolimus, furosemide, methadone, oral contraceptives, theophylline, TCAs, warfarin. May reduce effects of guanfacine. Reduced metabolism and or increased toxicity with chloramphenicol, felbamate, MAOIs, valproic acid. May enhance the nephrotoxic effects of methoxyflurane. Potentially Fatal: Additive sedation and/or respiratory depression with ethanol, sedatives, antidepressants, opioid analgesics, benzodiazepines and other CNS depressants. May decrease levels/effects of antiarrhythmic drugs e.g. disopyramide, propafenone, quinidine.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Phenobarbitone (Phenobarbital).
Use in pregnancy
[CONSULT YOUR DOCTOR] Phenobarbitone (Phenobarbital) is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Phenobarbitone (Phenobarbital) is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Monitor the baby for sleepiness, skin rash, and feeding issues.
Renal / hepatic impairment
[CAUTION] Phenobarbitone (Phenobarbital) should be used with caution in patients with kidney disease. Dose adjustment of Phenobarbitone (Phenobarbital) may be needed. Please consult your doctor. Use of Phenobarbitone (Phenobarbital) is not recommended in patients with severe kidney disease. [CAUTION] Phenobarbitone (Phenobarbital) should be used with caution in patients with liver disease. Dose adjustment of Phenobarbitone (Phenobarbital) may be needed. Please consult your doctor. Use of Phenobarbitone (Phenobarbital) is not recommended in patients with severe liver disease.
Common questions
She has problem of epilepsy from last two years Hello, epilepsy and seizures cannot be treated online without physically examining the child and detailed history. ?? ???? ?????? ?? ?????? ?? ?? ??? encorate Charon 200 500 tablet use krta hu kya iska koi solution h Jisse main completely thk ho jau Epilepsy requires regular treatment with anticonvulsants like encorate chrono for at least 3 years of seizure free period after which medicines may be tapered off unless seizures reappear. At present, there are no other effective treatment options. Want discontinued eptoin tablet Father had brain stroke so doctor is giving eptoin tablet 300 mg so I want ask that can tablet can remove or dose decreased ? wil depend on any recent seizures he had; and type of stroke; pls show 2 neuro I m taking 1.5gm sodium valporate,1.5 levectram, 1gm clobezam then also seizure r their at period of weekly is there alternate treatment in Ayurveda as every time at multiplying the doses at every visit As MRI eeg every tests r normal not aware of any ayurvedic medications for epilepsy is not my specialization. However you seems to have difficult to control (intractable) seizures plz follow doctors advice deligently for ur own welfare Fits, Seizures Earlier used to get temporal lobe but recently got grand mal https://www.1mg.com/otc/jiva-brahmi-tablet-otc329971One ?one tablet morning & evening after taking food .use this tablet along with your treatment Hi I am suffering from epilepsy from the past 1.5 years but before that I have no issues with my health the symptoms are I will get vomiting sensation from evening & heavy body pains & fits will comes only in early morning from 4 & 5 am i will get un concious for about 20 or 30 minutes & I will bite my tongue & after that I will have heavy nerve pains for a day or two from 5 days I am taking encorte 500 tablets between day & night before that I used to take homeopathy treatment Epilepsy is a central nervous system disorder (neurological disorder) in which nerve cell activity in the brain becomes disrupted, causing seizures or periods of unusual behavior, sensations and sometimes loss of consciousness. Medicines for epilepsy are initially recommended for at least 3 years of seizure free interval but may continue longer depending on recurrence. Epileptic patient needs to carry a warning card or a medical emergency bracelet with identification details, his/ her epilepsy status and what people can do if fit occurs in public place.