৳ 7/unit
Pack: ৳ 210
৳ 7/unit
Pack: ৳ 210
At a glance
Buspirone is an anxiolytic medication used in the treatment of anxiety disorder. It works by modulating serotonin receptors in the brain, reducing symptoms of anxiety such as irritability, restlessness, lack of concentration, fatigue, sweating, increased heart rate, and racing thoughts.
Indications
- Anxiety disorder
Pharmacology
Buspirone acts as a partial agonist at serotonin 5-HT1A receptors. It activates presynaptic 5-HT1A autoreceptors to regulate serotonin release and postsynaptic 5-HT1A receptors to produce anxiolytic effects. It has no direct interaction with GABA receptors, which explains its lower sedative profile compared to benzodiazepines.
Dosage
Adults (Anxiety Disorder): 10-15 mg/day orally, divided every 8-12 hours. Increase by 5 mg/day every 2-3 days to 15-30 mg/day. Max: 60 mg/day.
Hepatic impairment: Not recommended in severe hepatic impairment.
Renal impairment: Not recommended in severe renal impairment.
Note: Full efficacy may take 2-4 weeks.
Side effects
Common side effects: Nausea, headache, vomiting, dry mouth, sleepiness, dizziness, constipation, diarrhea, abdominal pain.
These side effects are usually mild and resolve over time.
Use in pregnancy
Generally considered safe during pregnancy (Category B). Animal studies have shown low or no adverse effects; limited human studies available.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Full efficacy may take 2-4 weeks to achieve.
- May cause dizziness and sleepiness; use caution while driving or doing anything requiring concentration.
- Avoid alcohol consumption (may cause excessive drowsiness).
- Do not stop abruptly without consulting your doctor.
- Avoid use in severe hepatic or renal impairment.
- Caution during pregnancy and lactation.
Overdose effects
Overdose symptoms: Nausea, vomiting, dizziness, drowsiness, pupillary constriction. Consult your doctor immediately if overdose is suspected.
Storage conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.