Carbizol 10

Carbimazole belongs to a group of medicine called anti-thyroid agents. It is used in the treatment of hyperthyroidism. It reduces the amount of thyroid hormones produced by the thyroid gland. Carbimazole may be used alone or in combination with other medicines. It can be taken with or without food. It should be taken exactly as prescribed by your doctor. Your doctor will decide the dose and how often you should take them. You should take this medicine regularly to get the most benefit from it. Do not stop taking the medicine even if you feel better unless the doctor tells you so. Taking this medicine may cause few common side effects such as skin rash, headache, skin pigmentation, and muscle pain or weakness. Let your doctor know if any of these do not go away with time or worse. Before using this medicine, inform your doctor if you have any problems with your liver or kidneys. You should also tell your doctor all the other medications you are taking. Pregnant and breastfeeding mothers should consult their doctors before using the medicine. Carbimazole is an anti-thyroid medication. It works by reducing the amount of thyroid hormones produced by the thyroid gland.

• Hyperthyroidism

Carbimazole is metabolised to methimazole which is responsible for its antithyroid action. It blocks the production of thyroid hormones by inhibiting thyroid peroxidase.

Adult Dose: Oral Hyperthyroidism, Adjunct to radio-iodine therapy, Grave's disease, Preparation for thyroidectomy Adult: Initially, 20-60 mg daily as a single or divided dose, reduced gradually once euthyroidism is achieved. Maintenance: 5-15 mg daily for at least 1 yr or 18 mth. Hepatic impairment: Severe: Contraindicated. Child Dose: Oral Hyperthyroidism; Adjunct to radio-iodine therapy; Preparation for thyroidectomy Child: 3-17 yr Initially, 15 mg daily, adjusted according to response.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Carbimazole may be taken with or without food, but it is better to take it at a fixed time.

Common: • Skin rash • Headache • Skin pigmentation • Pain • Joint stiffness • Nausea • Paresthesia (tingling or pricking sensation) • Hair loss

[UNSAFE] Carbimazole may cause side effects which could affect your ability to drive. Carbimazole is used for the treatment of hyperthyroidism. You may have to stop taking it for a while if you are also taking radio-iodine as a treatment for your overactive thyroid. It may affect the level of blood cells in your blood. Inform your doctor if you experience symptoms such as unexplained bruising or bleeding, sore throat, mouth ulcers, fever, or general illness. Stop taking Carbimazole and Inform your doctor if you develop symptoms of liver damage such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Hyperthyroidism due to nodular goitre.

Increased serum levels of theophylline or may develop toxicity. May enhance the effect of anticoagulants. Potentially Fatal: Increased sensitivity to warfarin in hyperthyroidism and careful control required as patient is rendered euthyroid.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Carbimazole. Please consult your doctor.

[CONSULT YOUR DOCTOR] Carbimazole is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[SAFE IF PRESCRIBED] Carbimazole is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. The American Thyroid Association also recommends monitoring babies for appropriate growth and development during routine pediatric check-ups.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Carbimazole in patients with kidney disease. Please consult your doctor. [CAUTION] Carbimazole should be used with caution in patients with liver disease. Dose adjustment of Carbimazole may be needed. Please consult your doctor. Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of Carbimazole is not recommended in patients with severe liver disease.

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