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At a glance

Indacaterol + Glycopyrronium + Mometasone Furoate is used as a maintenance treatment of asthma and to reduce asthma exacerbations in adults not adequately controlled with a maintenance combination of LABA and ICS.

Indications
  • Maintenance treatment of asthma in adults (not adequately controlled on LABA + ICS)
  • Reduction of asthma exacerbations
Pharmacology

Indacaterol is an ultra-LABA that stimulates intracellular adenyl cyclase to relax bronchial smooth muscle. Glycopyrronium is an ultra-LAMA that blocks acetylcholine action on airway smooth muscle to dilate airways. Mometasone Furoate is a synthetic corticosteroid with high affinity for glucocorticoid receptors and local anti-inflammatory properties; it inhibits release of leukotrienes and pro-inflammatory cytokines (IL-1, IL-5, IL-6, TNF-alpha).

Dosage

Adult Dose (Inhalation):

  • One inhalation capsule once daily
  • To be used with inhalation device only
  • Do not take more than one capsule in a day
Side effects

Most Common (over 52 weeks):

  • Nasopharyngitis
  • Upper respiratory tract infection
  • Headache
Use in pregnancy

Use in Pregnancy: Insufficient data on use in pregnant women; animal studies show mometasone furoate caused fetal malformations and decreased fetal survival; use only if expected benefit justifies potential risk to fetus.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings

Precautions:

  • Do not use to treat acute asthma symptoms or bronchospasm
  • If allergic reactions (angioedema, urticaria) occur, discontinue immediately
  • If pulse rate, blood pressure increase or symptoms occur, treatment may need to be discontinued
  • Monitor plasma glucose in diabetic patients
  • Rinse mouth or brush teeth after use to reduce risk of oropharyngeal candida infection
Overdose effects

No information on overdose.

Storage conditions

Keep below 30°C temperature, away from light & moisture; keep out of reach of children.

Indacaterol + Glycopyrronium + Mometasone Furoate — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.