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At a glance

Vinpocetine is a prescription medicine used in the treatment of Alzheimer's disease, stroke and memory loss in Parkinson's disease. It can also be used to treat age related memory loss and head injury.

Indications
  • Alzheimer's disease
  • Stroke
  • Dementia in Parkinson's disease
  • Age related memory loss
  • Head injury
  • Cerebral arteriosclerosis
  • Multi-infarct dementia
  • Hypertensive encephalopathy
  • Visual disorder
  • Hearing disorder
Pharmacology

Vinpocetine increases cerebral metabolism; it increases glucose and O2 consumption; improves cerebral hypoxia tolerance; shifts glucose metabolism to the energetically more favourable aerobic pathway; it elevates the ATP concentration and the ATP/AMP ratio in the brain, and elevates the cerebral norepinephrine, dopamine and serotonin levels.

Dosage

Adult Dose (Oral):

  • Tablet: 1-2 tablets thrice daily; maintenance dose is 1 tablet thrice daily

Adult Dose (IM):

  • Daily dose of 20-40 mg until improvement of symptoms (for not longer than 10 days), then oral treatment

Adult Dose (IV Infusion):

  • Daily starting dose is 20 mg in slow drip infusion (2 ampoules in 500-1000 ml infusion solution); can be increased to 1 mg/kg body weight during 3 to 4 days; continue for 10-14 days
Side effects

Common Side Effects:

  • Dizziness
  • Dryness in mouth
  • Flushing
  • Headache
  • Insomnia
  • Nausea
  • Stomach pain
  • Nervousness
  • Transient hypotension
  • Tachycardia
Use in pregnancy

Use in Pregnancy: Information not available; consult your doctor. Contraindicated in pregnancy.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Unknown if alters ability to drive; caution advised
  • Take with food or as suggested by your doctor
  • May make you feel dizzy; do not drive or do anything requiring mental focus
  • Avoid alcohol; may cause increased dizziness
  • Inform doctor if you suffer from any bleeding or heart disorder, hypertension or are taking anticoagulant medications
  • Consult doctor if pregnant or breastfeeding
Overdose effects

Symptoms: Transient hypotension, tachycardia.

Treatment: Supportive care.

Storage conditions

Store in a cool and dry place, protected from light and moisture.

Vinpocetine — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.