৳ 12.09/unit
Pack: ৳ 120.90
৳ 12.09/unit
Pack: ৳ 120.90
At a glance
Cilostazol is a medication used in the treatment of pain in the legs due to insufficient blood flow (intermittent claudication).
Indications
- Intermittent claudication (pain in legs due to insufficient blood flow)
Pharmacology
Cilostazol is a quinolinone derivative. The mechanism of action is to specifically inhibit cellular phosphodiesterase III (PDE III) and suppress cAMP degradation with a resultant increase in cAMP in platelets and blood vessels, leading to inhibition of platelet aggregation and vasodilation.
Dosage
Adult Dose (Oral): 100 mg twice daily (at least half an hour before or two hours after breakfast and dinner).
Dose Reduction: Consider 50 mg twice daily during coadministration of Fluconazole, Ketoconazole, Itraconazole, Erythromycin, Clarithromycin, Fluvoxamine, Fluoxetine, Nefazodone, Sertraline and Diltiazem.
Hepatic Dose: Moderate to severe: Use caution.
Renal Dose: CrCl <25 mL/min: Use caution.
Side effects
Common Side Effects:
- Headache
- Palpitations
- Abnormal stool
- Diarrhea
- Dizziness
- Chest pain
- Loss of appetite
- Bleeding
- Rash
- Vomiting
- Leg cramps
- Edema
Use in pregnancy
[CONSULT YOUR DOCTOR] Cilostazol may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Pregnancy Category C.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- [UNSAFE] Cilostazol may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
- Take it at least half an hour before or two hours after breakfast and dinner.
- It may take up to 12 weeks before your symptoms improve. Keep using the medication as directed.
- Consult your doctor if your symptoms do not improve after 4 weeks of treatment.
- Do not take it if you have heart failure, persistent chest pain at rest, or have had a heart attack or any heart surgery in the last six months.
- May increase risk of bleeding. Inform your doctor if you see pinpoint rash or blood in vomits, urine, or stool.
Overdose effects
Information on Cilostazol overdosage is not available. In case of overdose, symptomatic and supportive treatment should be given.
Storage conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.