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At a glance

Citalopram Hydrobromide is an SSRI antidepressant used for the treatment of depression and panic disorder.

Indications
  • Depression
  • Panic disorder
Pharmacology

Citalopram is bicyclic phthalane derivative and a selective serotonin re-uptake inhibitor, with little or no effect on noradrenaline, dopamine and GABA re-uptake. The inhibitory activity explains the antidepressant property of citalopram. It has no or very low affinity for 5-HT1AA, 5-HT2A, D1 and D2 receptors, α1, α2, β-adrenergic, histamine H1, muscarinic, cholinergic, benzodiazepine and opioid receptors.

Dosage

Depression (Adult): Initial: 20 mg/day (single dose in morning or evening), may increase to max 60 mg/day if necessary.

Panic Disorder (Adult): Initial: 10 mg/day, increased to 20 mg after 7 days; usual dose 20-30 mg/day; max 60 mg/day.

Elderly: Max 40 mg/day.

Hepatic Impairment (Mild-Moderate): 10 mg/day for first 2 weeks, max 20 mg/day.

Child: Contraindicated.

Side effects

Common Side Effects:

  • Erectile dysfunction
  • Insomnia (difficulty in sleeping)
  • Low sexual desire
  • Nausea
  • Restlessness
  • Upset stomach
  • Vomiting
  • Fatigue
  • Dry mouth
  • Increased sweating
  • Delayed ejaculation
  • Sleepiness

Serious Side Effects: Palpitations, orthostatic hypotension, confusion, amnesia, migraine, taste disturbance, tinnitus, seizures (overdose).

Use in pregnancy

[CONSULT YOUR DOCTOR] Citalopram Hydrobromide may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Pregnancy Category C.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • [UNSAFE] Citalopram Hydrobromide may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
  • It can take up to 8 to 12 weeks to see the medicine full effects on your mood.
  • Take it with food to avoid stomach upset.
  • It causes less drowsiness as compared to other antidepressant medications.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Inform your doctor if you experience decreased sex drive or difficulty having an orgasm.
  • Do not stop taking the medication suddenly without talking to your doctor.
Overdose effects

Overdose symptoms: Respiratory depression, convulsions. Doses as high as 2000 mg have been taken without signs of alteration in cardiovascular parameters.

Storage conditions

Keep below 30°C temperature, away from light & moisture. Keep out of reach of children.

Citalopram Hydrobromide — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.