Clindax Plus Gel 15gm1.2gm+.025gm/100gm
Rx- Company:
- Opsonin Pharma Limited
- Dosage form:
- Gel
- Pack size:
- 15gm tube
৳ 150/unit
Pack: ৳ 150
At a glance
Clindamycin Phosphate 1.2% + Tretinoin 0.025% Topical — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Clindamycin Phosphate 1.2% + Tretinoin 0.025% Topical is a combination of two medicines, used to treat acne, which appears as spots or pimples on your face, chest or back. This medicine works by attacking the germs that cause them and rejuvenates sun damaged skin. Clindamycin Phosphate 1.2% + Tretinoin 0.025% Topical is only meant for external use and should be used as advised by your doctor. You should normally wash and dry the affected area before applying a thin layer of the medicine. It should not be applied to broken or damaged skin. Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get it in these areas. It may take several weeks for your symptoms to improve, but you should keep using this medicine regularly. Do not stop using it as soon as your acne starts to get better. Ask your doctor when you should stop treatment. Side effects like burning sensation, irritation, itching, redness, dryness, skin peeling or skin inflammation (dermatitis) may be seen at the application site, in some people. These are usually temporary and resolve on their own. Consult your doctor if they bother you or do not go away. It is a safe medicine, but you should inform your doctor if you have any problems with your bowels (intestines), if you have ever had bloody diarrhea caused by taking antibiotics or if you are using any other medicines to treat skin conditions. Consult your doctor about using this medicine if you are pregnant or breastfeeding. Clindamycin Phosphate 1.2% + Tretinoin 0.025% Topical is a combination of two medicines: Clindamycin and Tretinoin, which treats pimples (acne). Clindamycin is an antibiotic which works by penetrating into the skin and killing acne-causing bacteria. Tretinoin is a form of vitamin A which reduces oil production in the skin, replenishes the skin and helps keep your pores open.
Indications
• Acne
Mechanism of action
Clindamycin: Antibacterial agent that binds to the 50S ribosomal subunits of susceptible bacteria and prevents elongation of peptide chains by interfering with peptidyl transfer, thereby suppressing protein synthesis; reduces surface fatty acids on skin; exact mechanism of action in treating acne unknown Tretinoin: Exact mechanism unknown; appears to cohesiveness of follicular epithelial cells with decrease microcomedo formation; also increases turnover of follicular cells to cause extrusion of comedones
Dosage
Adult Dose: Acne Vulgaris Topical Apply a pea-size amount of gel once daily preferably at bed time. Treatment should be continued for 12 weeks. Child Dose: 12 years: Apply a pea-size amount of gel once daily preferably at bed time.
Administration
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
Side effects
Common: • Application site reactions (burning, irritation, itching and redness) • Dryness • Skin peeling • Dermatitis
Precautions & warnings
No interaction found/established Retino AC Gel should be Applied as a thin layer onto clean, dry, unbroken skin affected by acne. Clean the area to be treated with water and a non-medicated soap, and let it dry for 20-30 minutes before applying the medicine. It may cause minor burning, stinging, or irritation when applied. Inform your doctor if this does not go away. Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get the cream in these areas. Avoid exposure to sunlight while using Retino AC Gel as it increases the sensitivity of your skin. Use protective measures such as sun-cream or protective clothing. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Contraindications
Contraindicated in patients with hypersensitivity to clindamycin or tretinoin or any of the ingredients of these medicine.
Drug interactions
Clindamycin: May enhance the action of neuromuscular blocking agents (e.g. atracurium). May antagonise the effects of parasympathomimetics. May competitively inhibit the effects of macrolides, ketolides, streptogramins, linezolid and chloramphenicol. Increased coagulation tests (prothrombin time/INR) and/or bleeding w/ vit K antagonists (e.g. warfarin, acenocoumarol, fluindione). Tretinoin: Enhances percutaneous absorption of minoxidil. Increased risk of fatal thrombotic complications with antifibrinolytic. Increased tretinoin concentrations with azole antifungals. Enhances peeling action of sulphur, resorcinol, benzoyl peroxide, salicylic acid. Increased photosensitivity with photosensitising medications eg, thiazides, tetracyclines, fluoroquinolones, phenothiazines and sulfonamides. Potentially Fatal: Increased risk of intracranial pressure with tetracyclines.
Food interactions
No interaction found/established
Use in pregnancy
[CONSULT YOUR DOCTOR] Clindamycin Phosphate 1.2% + Tretinoin 0.025% Topical may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Clindamycin Phosphate 1.2% + Tretinoin 0.025% Topical is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
No interaction found/established No interaction found/established
Common questions
Acne problem on face and chest Benzac ac gel at nightBenzac ac gel at night over pimples Pimple's acne problem and black spots Benzac ac gel at night Best cure for acne and get glowing skin Benzac ac gel on pimples Can anyone tell me for how long can i keep retino AC gel on face after its application I mean 20 min or 30 min or it can b kept the whole night? its and allopathic medicine, so better ask by ayurveda What i will do for acne and oily skin use benzac ac gel n ahaglo face wash I am having acne on my face with some white liquid inside it. After those pimples went many holes came there and many red marks can you please tell me some medicine to cure that holes. Doctor gave me erytop A cream but nothing happened. Apply benzac ac gel at night I am suffering from acne and pimples and black spot on my face . Please repely the suggestion about my peoblem . Try benzac ac 2.5 gel at night