Codyl

• Upper respiratory tract disorders
• Productive cough
• Allergic rhinitis
• Sneezing
• Cough & runny nose
• Nasal congestion

Triprolidine hydrochloride is a potent competitive histamine H1-receptor antagonist with antimuscarinic and mild sedative properties. Pseudoephedrine is both an alpha- and beta-adrenergic receptor agonist. It causes vasoconstriction via direct stimulation of alpha-adrenergic receptors of the respiratory mucosa and directly stimulates beta-adrenergic receptors causing bronchial relaxation and increased heart rate. Guaifenesin increases the volume and reduces the viscosity of tenacious sputum and is used as an expectorant for productive cough.

Adults and children over 12 years:

• 10 ml (2 teaspoonful) three times a day

Children 6-12 years:

• 5 ml (1 teaspoonful) three times a day

Children 2-5 years:

• 2.5 ml (1/2 teaspoonful) three times a day

Under 2 years:

• Physician's advice preferred

* Use as directed by the registered physician

Common Side Effects:

• CNS depression or excitation
• Sleep disturbance
• Hallucination (rare)
• Skin rashes
• Tachycardia
• Dryness of mouth, nose and throat
• Urinary retention (in men)

Use in Pregnancy: Widespread use without apparent ill consequence, but specific data lacking. Use with caution.

Precautions:

• May cause drowsiness - do not drive or operate machinery
• Avoid alcohol or other centrally acting sedatives
• Caution in hypertension, heart disease, diabetes, hyperthyroidism, elevated intraocular pressure and prostatic enlargement
• Do not use for persistent or chronic cough such as smoking, asthma or emphysema

Overdose: Drowsiness, irritability, restlessness, dizziness, gastrointestinal discomfort, respiratory depression, convulsions, tachycardia and hypertension may occur. Support respiration and control convulsions. Gastric lavage and bladder catheterization may be necessary.

Storage: Store below 25°C. Protect from light. Do not refrigerate.