Colitrol Plus
1200mg + .25mcgRx৳ 13/unit
Pack: ৳ 390
৳ 13/unit
Pack: ৳ 390
At a glance
Calcium Citrate + Calcitriol is a combination tablet used to prevent or treat low blood calcium levels, osteoporosis, osteomalacia, rickets, hypoparathyroidism, and latent tetany. It improves bone health and helps maintain calcium balance.
Indications
- Calcium deficiency
- Osteoporosis
- Osteomalacia
- Rickets
- Hypoparathyroidism
- Latent tetany
- Postmenopausal calcium supplementation
Pharmacology
Calcium citrate is a good source of calcium that is well absorbed on an empty stomach and does not cause constipation. Calcitriol is the active form of vitamin D3 that increases intestinal calcium and phosphate absorption and regulates bone mineralization. In chronic renal failure, calcitriol production is impaired, contributing to mineral metabolism abnormalities. Oral calcitriol administration compensates for this deficiency and reverses signs and symptoms of bone disease.
Dosage
Adults: 1-4 tablets daily (depending on clinical condition), with or without food, or as directed by the registered physician.
Note: Dose must be individualized based on serum calcium levels.
Side effects
Calcium-related side effects: Anorexia, constipation, flatulence, nausea, vomiting, hypercalcemia, hypophosphatemia, xerostomia, acid rebound, milk-alkali syndrome, coma, confusion, delirium, headache, lethargy.
Calcitriol-related side effects: Abdominal pain, apathy, increased BUN/creatinine, cardiac arrhythmia, constipation, dry mouth, dehydration, growth suppression, headache, hyperthermia, hypercalcemia, hypercholesterolemia, hypermagnesemia, hyperphosphatemia, hypertension, decreased libido, metallic taste, muscle/bone pain, nocturia, pruritus, psychosis, somnolence, weakness.
Use in pregnancy
May be unsafe during pregnancy (Category C). Use only as directed by a registered physician during pregnancy.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in hypercalcemia, malabsorption syndrome, heart disease, kidney disease, kidney stones, sarcoidosis, liver disease, Crohn's disease.
- Impaired calcium absorption in achlorhydria (common in elderly).
- Increased risk of hypercalcemia and hypercalciuria in hypoparathyroid patients on high doses of vitamin D.
- Caution in history of kidney stones and renal impairment.
- Risk of hypercalcemia with thiazide diuretics or excessive vitamin D.
Overdose effects
Overdose may cause hypercalcemia, hypercalciuria, hyperphosphatemia, milk-alkali syndrome. Symptoms: nausea, vomiting, constipation, confusion, coma. Consult your doctor immediately if overdose is suspected.
Storage conditions
Store in a cool and dry place below 25°C, protected from light and moisture. Keep out of reach of children.