Curon10mg/ml

Vecuronium Bromide belongs to a group of medicines called muscle relaxants. It is used along with general anesthesia or sedatives to provide skeletal muscle relaxation during surgical procedures. It is also used to facilitate emergency airway management in patients in intensive care. Vecuronium Bromide is administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. The most common side effects of this medicine include injection site reactions such as pain, redness, and swelling. Long-term use of this medicine may cause skeletal muscle weakness or even paralysis. You should let your doctor know if the side effects bother you. Your doctor may be able to suggest ways of preventing or reducing the symptoms. Before using it, to make sure it is safe for you, you should let your doctor know if you have any other medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine. Vecuronium Bromide relaxes the muscles by blocking the impulses from the nerves.

• Skeletal mucle relaxation during surgery

Vecuronium bromide inhibits depolarisation by blocking acetylcholine from binding to receptors on motor endplate.

Adult Dose: Intravenous Muscle relaxant in general anaesthesia; Facilitate endotracheal intubation; Facilitate mechanical ventilation in intensive care Adult: Initially, 80-100 mcg/kg by inj. Maintenance: 20-30 mcg/kg by inj or as continuous infusion at 0.8-1.4 mcg/kg/min. Surgical procedures after intubation w/ suxamethonium: 30-50 mcg/kg. Caesarean section: <100 mcg/kg. Surgery under halothane and neurolept anaesth: Initially, 150-300 mcg/kg. Child Dose: Intravenous Muscle relaxant in general anaesthesia; Facilitate endotracheal intubation; Facilitate mechanical ventilation in intensive care Child: 4 month: 80-100 mcg/kg by inj. Maintenance: 20-30 mcg/kg by inj or as continuous infusion at 0.8-1.4 mcg/kg/min. Neonatal surgery: <100 mcg/kg.

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Common: • Skin rash • Increased saliva production • Injection site reactions (pain, swelling, redness) • High blood pressure

[UNSAFE] Vecuronium Bromide may cause side effects which could affect your ability to drive. As Vecuronium Bromide is given as part of a general anesthetic, you may feel tired, weak or dizzy for some time afterward and this affects your ability to drive. Vecuronium Bromide is given as an injection by healthcare professionals only. It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Vecuronium Bromide affects you. You will be monitored continuously during the treatment to check the effect of the medicine. You will be given artificial ventilation until you are able to breathe on your own.

Hypersensitivity to vecuronium or bromide.

Increases neuromuscular blockade with volatile anaesthetic agents (halothane, ether, enflurane, isoflurane, methoxyflurane, propofol and cyclopropane), fentanyl, other non-depolarising muscle relaxants, prior admin of succinylcholine, tetracyclines, polymyxins, diuretics, thiamine, MAOIs, bacitracin, colistin, sodium colistimethate, acylaminopenicillins, aminoglycoside antibiotics, high dose metronidazole, protamine, beta-adrenergic blocking agents, calcium antagonists e.g. verapamil, and Mg. Decreased neuromuscular blockade with anticholinesterases, prior chronic admin of corticosteroids, phenytoin, carbamazepine, noradrenaline, azathioprine, theophylline, calcium chloride.

[UNSAFE] It is unsafe to consume alcohol with Vecuronium Bromide.

[CONSULT YOUR DOCTOR] Vecuronium Bromide may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Vecuronium Bromide is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[SAFE IF PRESCRIBED] Vecuronium Bromide is safe to use in patients with kidney disease. No dose adjustment of Vecuronium Bromide is recommended. However, inform your doctor if you have any underlying kidney disease. [CAUTION] Vecuronium Bromide should be used with caution in patients with liver disease. Dose adjustment of Vecuronium Bromide may be needed. Please consult your doctor.

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