osudhkosh

Cynomin250mcg/ml

Rx
Dosage form:
Injection
Pack size:
Injection
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৳ 4.51/unit

Pack: ৳ 4.51

At a glance

Cyanocobalamin (Vitamin B12) is an essential vitamin used for the treatment of pernicious anemia, vitamin B12 deficiency, macrocytic anemia, and other related conditions.

Indications
  • Pernicious anemia
  • Vitamin B12 deficiency (low intake from food)
  • Thyrotoxicosis
  • Hemorrhagic anemia
  • Malignancy-associated anemia
  • Liver or kidney disease-related B12 deficiency
  • Post-gastric bypass surgery or gastrectomy
  • Gluten enteropathy or sprue
  • Folic acid deficiency
  • Macrocytic anemia
Dosage

Adult Dose (IM - Pernicious or Macrocytic Anemia): 250-1000 mcg, given on alternate days for 1-2 weeks, then 250 mcg weekly until blood count returns to normal. Maintenance doses: 1000 mcg, given every month.

Hepatic Dose: Increased requirement in hepatic impairment.

Renal Dose: Increased requirement in renal impairment.

Side effects

Common Side Effects (>10%):

  • Arthralgia (joint pain) (12%)
  • Dizziness (12%)
  • Headache (12%)
  • Nasopharyngitis (12%)

Other Side Effects:

  • Anaphylaxis
  • Angioedema
  • Congestive heart failure
  • Peripheral vascular disease
  • Pulmonary edema
  • Diarrhea
  • Dyspepsia
  • Polycythemia vera
  • Sore throat
  • Nervousness
  • Rhinitis
  • Glossitis
  • Hypoesthesia
Precautions & warnings
  • Intensive treatment of B12-deficient megaloblastic anemia may cause hypokalemia and sudden death.
  • Nasal disease: Defer use until symptoms resolve.
  • Use with caution in patients with Leber optic nerve atrophy.
  • Thrombocytosis may occur with treatment of severe vitamin B12 megaloblastic anemia.
Cyanocobalamin (Vitamin B12) — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.