Dabiran150mg

Dabigatran is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain and heart. Dabigatran is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It can be taken with or without food, but it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise and losing weight if you need to. The most common side effect of Dabigatran are stomach upset and bleeding more easily than normal, for example having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include headache, seizures, allergic reactions, changes to your eyesight, and tiredness. Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, regular blood test (PT-INR) is not required while taking this medicine. Dabigatran is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.

• Stroke prevention • Deep vein thrombosis • Pulmonary embolism

Dabigatran is a competitive, selective, reversible direct inhibitor of thrombin. It inhibits thrombin-induced platelet aggregation and the conversion of fibrinogen to fibrin thus preventing thrombus formation.

Adult Dose: Oral Prophylaxis of postoperative venous thromboembolism Adult: Initially, 110 mg given w/in 1-4 hr after surgery followed by 220 mg once daily for a total of 10 days after (knee replacement) or 28-35 after (hip replacement). Reduce dose to 150 mg once daily if given concurrently w/ amiodarone, verapamil or quinidine. Elderly: >75 yr Initially, 75 mg given w/in 1-4 hr after surgery followed by 150 mg once daily for a total of 10 days after (knee replacement) or 28-35 after (hip replacement). Atrial fibrillation Adult: 150 mg bid, reduce dose to 110 mg bid if given concurrently w/ verapamil. Elderly: >75 yr 110 mg bid. Renal Dose: Prophylaxis of postoperative venous thromboembolism Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Contraindicated. 30-50 Initial: 75 mg w/in 1-4 hr after surgery followed by 150 mg once daily for a total of 10 days after (knee replacement) or 28-35 days after (hip replacement). Max: 75 in patients taking w/ verapamil. Atrial fibrillation Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Contraindicated. 30-50 110 mg bid.

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Dabigatran may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Dabigatran, please consult your doctor.

Common: • Bleeding • Nausea • Stomach pain • Indigestion

[SAFE] Dabigatran does not usually affect your ability to drive. Take it as per dose and duration suggested by your doctor. Dabigatran increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g., football and wrestling). If you are going to have a surgery or dental treatment, you may be asked to stop taking Dabigatran temporarily. Your doctor may get a blood test done to check kidney function before starting treatment with this medicine. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Do not stop taking the medication without talking to your doctor.

Active pathological bleeding or patient at high risk for bleeding. Patients w/ prosthetic heart valve. Severe renal impairment. Concomitant use w/ antiplatelets, other anticoagulants, thrombolytics, dronedarone, P-glycoprotein inducers (e.g. carbamazepine, rifampicin, phenytoin and St John's wort) and P-glycoprotein strong inhibitors (e.g. ciclosporin, systemic ketoconazole, itraconazole, and tacrolimus).

May increase risk of bleeding w/ NSAIDs. Clarithromycin may increase the serum levels of dabigatran. Potentially Fatal: P-glycoprotein inducers (e.g. carbamazepine, rifampicin, and phenytoin) decreases systemic exposure of dabigatran. P-glycoprotein strong inhibitors (e.g. ciclosporin, systemic ketoconazole, itraconazole, and tacrolimus) and dronedarone increases systemic exposure of dabigatran. Increased bleeding risk w/ antiplatelets, other anticoagulants and thrombolytics.

[UNSAFE] It is unsafe to consume alcohol with Dabigatran.

[CONSULT YOUR DOCTOR] Dabigatran may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Dabigatran is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[CAUTION] Dabigatran should be used with caution in patients with severe kidney disease. Dose adjustment of Dabigatran may be needed. Please consult your doctor. Use of Dabigatran is not recommended in patients with severe kidney disease. [CAUTION] Dabigatran should be used with caution in patients with liver disease. Dose adjustment of Dabigatran may be needed. Please consult your doctor.

Deep vein thrombosis , swelling nd painful in both leg. You need to take a surgical consultation Looking for a specialist in Deep vein thrombosis preferably in Kochi See a vascular surgeon In road accident head and small intestine got injured . 15 stiches on head and operation of 1 inch diameter of intestine . Now spo2 level is dropping to 70% after 1 hour of removing oxygen mask Get checked for pulmonary embolism or pneumothorax Is there any subsitute medicine for PRADAXA 110 mg Yes but this is the safe option Need continued prescription for a year for anti coagulant Pradaxa 110mg , two capsules a day as per attached prescription from Manipal hospital bangalore This prescription renewal is required for purpose of buying medicine online as medicine is advised life long Need to consult physician near u can&#x27;t prescribe online My mother suffered a stroke leading to clot in brain on 9 Feb 2017. Doctor prescribed Pradaxa 110 to be taken twice a day. She suffers from Atrial Fibrillation. I wish to know how long should she take anti coagulant and if it has to be taken regularly then is there any cheaper alternative to Pradaxa. If affordability is not an issue it should be taken lifelong GE my self v.k tiwari mbbs md i feel the patient information above is there any blood test for diagnosed pulmonary edema and pulmonary embolism Dear Sir There is no specific blood test for diagnosing pulmonary edema and embolism Heavy headache left side only. Two year before I&#x27;ll take pradaxa 150mg tablets. But now I didn&#x27;t take that. Pls upload reports of proper resolution