Darbagen 100
Rx- Generic:
- Darbepoetin alfa
- Company:
- ACI Limited
- Dosage form:
- Sc Injection
- Pack size:
- Pre-Filled Syringe
৳ 9,090/unit
Pack: ৳ 9,090
At a glance
Darbepoetin alfa is an erythropoiesis-stimulating agent (ESA) used for the treatment of anemia due to chronic kidney disease or cancer chemotherapy.
Indications
- Anemia due to Chronic Kidney Disease (dialysis and non-dialysis patients)
- Anemia due to cancer chemotherapy
Dosage
Adult - CKD (dialysis & non-dialysis): Initial dose 0.45 mcg/kg IV/SC once weekly; or 0.75 mcg/kg every 2 weeks; or 1.5 mcg/kg once monthly. Initiate when Hb <10 g/dL.
Child (≥1 year): 0.45 mcg/kg IV/SC once weekly; or 0.75 mcg/kg every 2 weeks (non-dialysis).
Chemotherapy-induced anemia: 500 mcg (6.75 mcg/kg) once every 3 weeks SC; or 2.25 mcg/kg once weekly SC.
Side effects
Common: Hypertension, stroke, thromboembolic events, convulsions, allergic reactions, rash/erythema, and Pure Red Cell Aplasia (PRCA).
Precautions & warnings
Use with caution in patients with controlled hypertension, seizures, PRCA, or allergy history. Monitor blood pressure regularly. Inform doctor if symptoms of very high blood pressure (severe headache, vision problems, nausea, vomiting, seizures) occur. Discontinue if shortness of breath or skin rash develops.