৳ 7.03/unit
Pack: ৳ 7.03
৳ 7.03/unit
Pack: ৳ 7.03
At a glance
Gemfibrozil is a lipid-lowering medicine used to reduce triglycerides and cholesterol.
Indications
- Type IIa, IIb, III, IV and V hyperlipoproteinemia
- High triglycerides
- High cholesterol
Pharmacology
Gemfibrozil is an anti-lipemic agent. Gemfibrozil decreases serum triglycerides in healthy individuals and patients with hyper-triglyceridemia. It decreases very low-density lipoprotein (VLDL)- triglyceride concentration and to a lesser extent, LDL triglyceride concentration. Gemfibrozil usually increases the HDL-cholesterol fraction in healthy individuals and patients with hyperlipoproteinemia, an action that may be beneficial in slowing the progression of atherosclerosis and in reducing the risk of coronary heart disease.
Dosage
Adult Dose:
- 1.2 gm daily in 2 divided doses (30 minutes before morning and evening meal)
- Dosage range: 0.9-1.5 gm daily
Children: Safety and efficacy not established
Renal Impairment (Mild to moderate): Use with caution
* Use as directed by the registered physician
Side effects
Common Side Effects:
- Abdominal and epigastric pain
- Dyspepsia
- Pruritus
- Rash
- Headache
- Dizziness
- Blurred vision
- Myalgia (rare)
- Increased liver enzymes
- Diarrhea
- Flatulence
Use in pregnancy
Use in Pregnancy: May be unsafe during pregnancy. Animal studies have shown harmful effects.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Avoid alcohol consumption.
- Regular liver function, blood counts and renal activity tests recommended.
- Inform doctor if you experience muscle pain, tenderness, cramps or weakness (especially with fever).
- Caution in patients with gallstones.
Overdose effects
Overdose: Overdose may cause gastrointestinal disturbances. Symptomatic treatment should be given.
Storage conditions
Storage: Keep below 30°C, away from light and moisture. Keep out of reach of children.