Dieta Plus 430mg+4mg

Glimepiride + Pioglitazone is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in proper utilisation of insulin, thereby lowering the blood sugar levels. Glimepiride + Pioglitazone should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia). Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol or upon skipping a meal. Monitor your blood sugar levels regularly while taking it. Other common side effects of this medicine include nausea, taste changes, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and respiratory tract infection. Before taking this medicine, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects. Glimepiride + Pioglitazone is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.

• Type 2 diabetes mellitus

Pioglitazone, a thiazolidinedione, reduces blood glucose by improving target cell response to insulin w/o increasing pancreatic insulin secretion and is dependent on the presence of insulin for activity. Glimepiride, a sulfonylurea, stimulates insulin release from the pancreatic beta-cells. It also reduces glucose output from the liver and increases insulin sensitivity at peripheral target sites.

Adult Dose: Oral Type 2 diabetes mellitus Adult: 30 mg/2 mg, OR 30 mg/4 mg: Initially, 1 tab once daily then titrate gradually as needed. Elderly: Should start w/ glimepiride 1 mg/day prior to initiating pioglitazone + glimepiride combination. Hepatic Impairment 1 mg/day glimpiride PO prior to initiating glimepiride/pioglitazone; titrate conservatively to avoid hypoglycemia Baseline ALT 2.5 xULN: Do not initiate ALT >3 xULN or jaundice after initiating therapy: Discontinue Renal Dose: Renal Impairment CrCl 22 mL/min: 30 mg/2 mg or 30 mg/4 mg PO qDay initially

Use it as advised by your doctor or check the label for directions before use. Glimepiride + Pioglitazone is to be taken with food.

Common: • Hypoglycemia (low blood glucose level) • Nausea • Taste change • Diarrhea • Stomach pain • Headache • Edema (swelling) • Weight gain • Blurred vision • Bone fracture • Respiratory tract infection

[CAUTION] Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur. Take it with food to lower your chance of having an upset stomach. It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

History of allergic reaction to sulfonamide derivative. Patient w/ established CHF (NYHA class III or IV). Not intended for treatment of type 1 DM or diabetic ketoacidosis.

Increased plasma levels w/ CYP2C8 inhibitors (e.g. gemfibrozil) and CYP2C9 inhibitors (e.g. fluconazole). Decreased plasma levels w/ CYP2C8 inducers (e.g. rifampicin). Colesevelam may reduce the max plasma concentration and total exposure of glimepiride. Concominant use w/ oral miconazole may lead to severe hypoglycaemia.

[UNSAFE] It is unsafe to consume alcohol with Glimepiride + Pioglitazone.

[CONSULT YOUR DOCTOR] Glimepiride + Pioglitazone may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Glimepiride + Pioglitazone is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Monitor the breastfed baby’s blood sugar during treatment with Glimepiride + Pioglitazone

[CAUTION] Glimepiride + Pioglitazone should be used with caution in patients with kidney disease. Dose adjustment of Glimepiride + Pioglitazone may be needed. Please consult your doctor. Use of Glimepiride + Pioglitazone is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine. [CAUTION] Glimepiride + Pioglitazone should be used with caution in patients with liver disease. Dose adjustment of Glimepiride + Pioglitazone may be needed. Please consult your doctor. Use of Glimepiride + Pioglitazone is not recommended in patients with severe liver disease.

I am taking gluconorm pg 2 fort one a day I f it is keeping your fasting/Pp/Hba1c kidney /liver functions acceptable then you can continue same. My father take gluconorm pg-2. Please consult the alternative. Needs to see the patient for priscribing medicine as complete medical history and sugar level variation chart required. I am a diabetic and using Gluconorm PG-2 tablet since 3 years. The results for controlling diabetic is good. However, I have read some where that using Gluconorm PG-2 tablet for more than a year is likely to have bladder cancer. Is it correct? Can your prescribe any alternative medicine. its the pioglitazone that can cause bladder cancerbut its frequency is too less i am diabetic for last 3 years ,ED and lack libido,advice,currently eating gluconorm PG 2 Dear sir for the time being you can take Lycopodium 30, 04 drops in half cup water thrice daily for a month, but as this case needs supervision, discussion and examination you need to visit a sexologist so that he can discuss your case in detail, get some investigations, do examination and guide you accordingly, My fasting sugar level is about 150 whereas after meals 250 approximately after talking Gluconorm PG 2 Needs to make some dose adjustment in the medicine you are taking, if you are not having any diet failure. So confirm about your diet failure first and consult your doctor . I am a diabetic since last 8-9 years using Gluconorm PG 2- 1 Tab daily as per advice since last 2.5 years, also using Tazloc AM-1 tab for BP and Thyronorm .25 -1. My average Fasting Sugar is 123-132 varies. Shall I continue Gluconorm PG-2 as I have apprehension of its side effect for prolonged use. Please advice. It is easy to maintain sugar levels.You should have dedication to do regular exercise and maintain your calories intake which your diabetic educator have be told.As only medicine can't help for long time.secondly you you take proper dose of medicine which doctor has adjusted for you as per your reports.thirdly time visit to doctor and do all routine investigations. I have type 2 diabetes since 2 years. Since 6 months, my sugar level remains between 130-150. I take doctor prescribed Gluconorm tablet twice a day. Is it enough? I think you should follow diabatic diet chart which will help you to your sugar level in normal limit with tab. gluconorm Prescription for buying medicine Ozomet PG -1 Ozomet PG-2 Zyloric 100mg A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET