৳ 8/unit
Pack: ৳ 80
৳ 8/unit
Pack: ৳ 80
At a glance
Tiotropium is a long-acting anticholinergic bronchodilator used for the long-term treatment of COPD and asthma. It relaxes airway muscles by blocking M3 receptors and widens airways.
Indications
- Chronic obstructive pulmonary disease (COPD)
- Asthma
Pharmacology
Tiotropium binds to M1-M5 muscarinic receptors, inhibiting acetylcholine action at M3 receptors, leading to relaxation of respiratory smooth muscle and bronchodilation. Its effect lasts over 24 hours.
Dosage
Adult Dose (Inhalation):
- Inhaler: 2 puffs (18 mcg) once daily
- Inhalation capsule: 1 capsule (18 mcg) once daily via inhaler device, at the same time each day
Side effects
Common Side Effects:
- Blurred vision
- Increased heart rate
- Dry mouth
- Upper respiratory tract infection
- Constipation
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies show harmful effects; use only if clearly needed; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Do not use for sudden breathing problems or asthma attacks
- Take at the same time each day
- Gargle with warm water after each inhalation (to avoid oral fungal infections)
- Take the first dose under medical supervision (may cause bronchospasm)
- For dry mouth, increase water intake, use sugarless candy, maintain oral hygiene
Overdose effects
No systemic anticholinergic effects following single inhaled doses up to 282 mcg; bilateral conjunctivitis and dry mouth with repeated 141 mcg daily doses; provide symptomatic treatment.
Storage conditions
Store below 30°C, away from direct sunlight and heat; keep out of reach of children.