৳ 251.94/unit
Pack: ৳ 251.94
৳ 251.94/unit
Pack: ৳ 251.94
At a glance
Dobutamine is a sympathomimetic agonist used for short-term treatment of heart failure and low blood pressure by increasing the pumping capacity of the heart.
Indications
- Heart failure (cardiac decompensation)
- Cardiogenic shock
- Hypoperfusion states
Pharmacology
Dobutamine Hydrochloride is a direct-acting inotropic agent whose primary activity results from stimulation of cardiac adrenergic receptors. It increases stroke volume and cardiac output and decreases ventricular filling pressure and total systemic and pulmonary vascular resistances.
Dosage
Adults and Children: Initially 0.5-1 mcg/kg/min IV continuous infusion, then 2-20 mcg/kg/min; max 40 mcg/kg/min. Adjust according to patient's BP, heart rate, cardiac and urine output.
Side effects
Common: High blood pressure, insomnia.
Other: Increased heart rate, ventricular ectopic activity, hypotension, infusion site reactions.
Use in pregnancy
Generally considered safe during pregnancy (animal studies show low or no adverse effects; limited human studies).
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
May affect driving ability. Close monitoring of heart rate, rhythm, arterial blood pressure, and infusion rate is required. Caution in pregnancy and lactation.
Overdose effects
Overdose may cause tachycardia, arrhythmia, hypertension, angina. Seek medical attention.
Storage conditions
Keep below 30°C temperature, away from light & moisture. After dilution, stable for 24 hours.