Dorubin20mg/4ml

Daunorubicin is used for the treatment of blood cancer (leukemia). It works by interfering with the growth of cancer cells, which are eventually destroyed. Daunorubicin is given under the supervision of a healthcare professional and should not be self-administered. It might be given as a single therapy or in combination with some other medication. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage. The most common side effects of this medicine include nausea, vomiting, low platelet count, ulcer, loss of appetite and difficulty while breathing. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, ECG, and physical examinations both before and during treatment with this medicine. Daunorubicin is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

• Blood cancer

Daunorubicin forms a stable complex with DNA and interferes with the nucleic acid synthesis. It is a cell-cycle nonspecific agent, but its cytotoxic effects are mostly marked in the S-phase. It also has immunosuppressant and antibacterial effects.

Adult Dose: Acute Nonlymphocytic Leukemia In combination with cytarabine 100 mg/m²/day IV for 7 days first course, for 5 days subsequent courses 60 years old: 30 mg/m² IVP days 1, 2, 3 first course; days 1, 2 subsequent courses Acute Lymphocytic Leukemia 45 mg/m² IVP days 1, 2, 3 Hepatic Impairment 3 mg/dL serum bilirubin: 50% of regular dose Child Dose: Acute Nonlymphocytic Leukemia 2 years old or >0.5 m² BSA: 25 mg/m² IVP qWeek Acute Lymphocytic Leukemia 2 years old or >0.5 m² BSA: 25 mg/m² IVP qWeek Renal Dose: Renal Impairment >3 mg/dL serum creatinine: Administer 50% regular dose

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Common: • Nausea • Vomiting • Low blood platelets • Ulcer • Abdominal pain • Loss of appetite • Decreased white blood cell count • Hair loss • Fever • Decreased blood cells (red cells, white cells, and platelets) • Fatigue • Anemia (low number of red blood cells) • Chills • Diarrhea • Mucosal inflammation • Febrile neutropenia • Stomatitis (Inflammation of the mouth) • Breathing problems

[UNSAFE] Daunorubicin may cause side effects which could affect your ability to drive. You must undergo careful examination of functioning of the heart as daunorubicin is known to cause life-threatening heart problems due to damage to heart muscles (myocardium). Daunorubicin should be used cautiously is elderly, children, and patients with high blood pressure (manifest arterial hypertension) due to increased risk of developing heart complications. You may be frequently examined for complete blood-count (blood cells, proteins, hemoglobin), kidney, liver and heart function before and during the course of treatment. Tell your doctor if you have had, have an ongoing or scheduled radiation therapy or X-ray of the chest area. Daunorubicin increases the risk of reactions at the site of radiation therapy (or risk of heart problem if the chest area is involved) and should be used cautiously. You should be monitored for worsening of infections and development of life-threatening infections (e.g. viral infections like herpes zoster) as daunorubicin is known to suppress the activity of the immune system. Liposomal preparation of daunorubicin is not recommended for use in children <18 years. Before starting daunorubicin treatment, make sure that you are free from any side effects of previous chemotherapy (inflammation of the mouth, abnormal blood cell counts and generalized infections). Both partners should take extreme care to avoid pregnancy while on daunorubicin therapy and consult your doctor if you get to know that you are pregnant.

Heart failure. Pregnancy, lactation.

Increased risk of cardiotoxicity when used with cyclophosphamide. Increased risk of hepatic toxicity when used with hepatotoxic drugs e.g. high-dose methotrexate. Potentially Fatal: Immunisation with live vaccines is not recommended. Concurrent radiation may lead to increased radiation reaction.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Daunorubicin. Please consult your doctor.

[CONSULT YOUR DOCTOR] Daunorubicin is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[UNSAFE] Daunorubicin is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

[CAUTION] Daunorubicin should be used with caution in patients with kidney disease. Dose adjustment of Daunorubicin may be needed. Please consult your doctor. Use of Daunorubicin is not recommended in patients with severe kidney disease. [CAUTION] Daunorubicin should be used with caution in patients with liver disease. Dose adjustment of Daunorubicin may be needed. Please consult your doctor. Use of Daunorubicin is not recommended in patients with severe liver disease.

Can blood cancer patients 1st stage do sex with normal girl Sir a blood cancer patients do sex with normal girl can any problem or cause doing with girl or side effect give suggestions Thanks Wait till blood cancer gets cured. Blood Cancer. Is there any medicine to cure blood cancer. Case has to be seen in person What is t-cell all ??? And treatment This is my mother first born mero report Now the blast is less then 5% after 1 month treatment This is blood cancerShe is in remission I seem to have lung cancer , becoz all the symptoms are same as lung cancer. I test my blood, they suggests me that it is highly probable to lung cancer. Sir what can i do now. This is in preliminary stage Do you think that lung cancer is diagnosed from blood please tell me the symptoms of blood cancer Blood cancer can have following symptoms Fever Bleeding Lymphadenopathy Patechia How to come blood. Cancer ,,,, Dear PATIENT specify your question. What is the complete treatment for blood cancer Blood cancer has 4 types, do you know which type u r asking Medicine for first stage blood cancer Need to consult face to face , kindly consult to ayurvedic doctor at your local city.