৳ 110/unit
Pack: ৳ 110
৳ 110/unit
Pack: ৳ 110
At a glance
Magnesium Sulphate injection is used for decreased magnesium levels in blood and for controlling seizures in pregnant women with high blood pressure. It widens blood vessels in the brain and improves blood supply to nerve cells.
Indications
- Seizures in pregnant women with high blood pressure (eclampsia/pre-eclampsia)
- Decreased magnesium levels in blood (hypomagnesemia)
- Torsades de pointes
- Barium poisoning
- Cerebral edema
Pharmacology
Magnesium sulfate decreases acetylcholine levels in motor nerve terminals and acts on the myocardium by decreasing SA node impulse formation and prolonging conduction time.
Dosage
Hypomagnesemia (IV): 1-2 g over 5-60 mins, then 0.5-1 g/hr
Torsades de pointes: 1-2 g over 5-60 mins
Eclampsia: Loading: 4-5 g over 10-15 mins, then 1 g/hr IV OR IM 4-5 g every 4 hours; max 30-40 g/24 hr
IM (Mild deficiency): 1 g 6 hourly for 4 doses
Side effects
Common Side Effects:
- Injection site reactions (pain, swelling, redness)
- Nausea, vomiting
- Flushing, thirst
- Hypotension, drowsiness, confusion
Use in pregnancy
Use in Pregnancy: Magnesium Sulphate injection is unsafe during pregnancy (Category D); definite evidence of risk to the fetus. Used under supervision in eclampsia.
Pregnancy Category: D — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in patients with bleeding disorders, heart block, kidney problems, or breathing problems
- Caution if taking nervous system, heart, or hypertension medications
- Monitor serum-magnesium concentrations
- Caution in pregnancy
Overdose effects
Overdose causes magnesium toxicity - breathing difficulty, loss of reflexes; treat with calcium gluconate and supportive care.
Storage conditions
Store in a cool and dry place; keep out of reach of children.