oshudhkosh

Elivier 500

Rx
Generic:
Nabumetone
Dosage form:
Tablet
Pack size:
Strip (10 Tablet)

৳ 15/unit

Pack: ৳ 150

At a glance

Nabumetone — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Nabumetone is a pain relieving medicine. It effectively alleviates pain and inflammation in conditions like rheumatoid arthritis and osteoarthritis. Nabumetone should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Inform your doctor if you have any history of heart disease or stroke. Vomiting, stomach pain, nausea and indigestion are some of the common side effects that might be observed on taking this medicine. It may also cause dizziness, drowsiness or visual disturbances. Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment. Long term use may lead to serious complications such as stomach bleeding and kidney problems. Nabumetone is a non-steroidal anti-inflammatory drugs (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

Indications

• Pain relief

Mechanism of action

Inhibits synthesis of prostaglandins in body tissues by inhibiting at least 2 cyclooxygenase (COX) isoenzymes, COX-1 and COX-2 May inhibit chemotaxis, alter lymphocyte activity, decrease proinflammatory cytokine activity, and inhibit neutrophil aggregation; these effects may contribute to anti-inflammatory activity

Dosage

Adult Dose: Oral Adult Osteoarthritis 1g PO once daily initially; maintenance: 1-2 g/day PO in single daily dose or divided q12hr; not to exceed 2 g/day Rheumatoid Arthritis 1 g PO once daily initially; maintenance: 1-2 g/day PO in single daily dose or divided q12hr; not to exceed 2 g/day Elderly: 500 mg daily may be adequate in certain patients. Max: 1 g daily. Child Dose: Not recommended Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation 30-49 Max initial dose: 750 mg once daily. Increase if needed to a max dose of 1.5 g daily. <30 Max initial dose: 500 mg once daily. Increase if needed to a max dose of 1 g daily.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nabumetone is to be taken with food.

Side effects

Common: • Vomiting • Stomach pain/epigastric pain • Nausea • Indigestion • Loss of appetite • Diarrhea • Heartburn

Precautions & warnings

[UNSAFE] Nabumetone may cause side effects which could affect your ability to drive. As may feel dizzy, tired, have problems with your vision or have headaches after taking Nabumetone and this may affect your ability to drive. You have been prescribed Nabumetone to relieve pain and inflammation. Take it with food or milk to prevent upset stomach. Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems. It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration. Avoid consuming alcohol while taking Nabumetone as it can cause excessive drowsiness and increase your risk of stomach problems. Inform your doctor if you have a history of heart disease or stroke. Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.

Contraindications

Absolute: Aspirin allergy, severe renal impairment; perioperative pain in setting of coronary artery bypass graft (CABG) surgery Relative: Duodenal/gastric/peptic ulcer, stomatitis, systemic lupus erythematosus, ulcerative colitis, late pregnancy (may cause premature closure of ductus arteriosus)

Drug interactions

Antihypertensive effects of hypotensive agents may be reduced. May increase ciclosporin levels. Increased risk of seizures with fluoroquinolones. May reduce efficacy of diuretics. May diminish the cardioprotective effect of acetylated salicylates. Alcohol may enhance gastric mucosal irritation. Potentially Fatal: Increased risk of bleeding with anticoagulants (e.g. warfarin, heparin, LMWHs) and antiplatelet agents (e.g. ticlopidine, clopidogrel, aspirin, abciximab, dipyridamole, eptifibatide, tirofiban). Increased risk of GI ulceration with corticosteroids. Severe bone marrow suppression, aplastic anaemia and GI toxicity may occur with methotrexate.

Food interactions

[UNSAFE] It is unsafe to consume alcohol with Nabumetone.

Use in pregnancy

[CONSULT YOUR DOCTOR] Nabumetone may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Use in lactation

[CONSULT YOUR DOCTOR] Nabumetone is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Renal / hepatic impairment

[CAUTION] Nabumetone should be used with caution in patients with kidney disease. Dose adjustment of Nabumetone may be needed. Please consult your doctor. Kidney function tests and some other blood tests may advised when you will start with this therapy and then at regular intervals while you are taking this medicine. [CAUTION] Nabumetone should be used with caution in patients with liver disease. Dose adjustment of Nabumetone may be needed. Please consult your doctor. Use of Nabumetone is not recommended in patients with severe liver disease.

Common questions

Plz dr. suggest me periods pain reliefer tablet which available easily at store. You can take govern tablets for pain relief Dear doctor my wife is 4 month pregnant since afternoon she is suffering from head ache , can you please suggest me what should be done Tablet Crocin pain relief can. E given I have piles problem for last 30 days and i just want to know which medicine or tablet i should take right now which can relief my pain and bleeding. Kindly suggest me tablet zerodol for pain relief Sits bath Consult a surgeon Avoid constipation Hip pain ,I taking tablet naproxen 500mg But motion come blood You stop Naproxen, ask your consultant to change the medicine. Severe tooth pain and swelling what tablet can be used for emergency just for pain relief you can take ketorol dt 2 tabs dissolved in half glass of water. further you must consult a dentist for the right treatment. One of my teeth is sensitive. It some times pains sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief Pain in teeth age 15 male pain relief tablet Tab Dolo 650 1 SOS fever and 2 months pregnant can take combiflan No take Crocin for pain relief

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.