৳ 40/unit
Pack: ৳ 400
৳ 40/unit
Pack: ৳ 400
At a glance
Ambrisentan is indicated for the treatment of Pulmonary Arterial Hypertension (PAH) (WHO Group 1) to improve exercise ability and delay clinical worsening.
Indications
Treatment of Pulmonary Arterial Hypertension (PAH) (WHO Group 1) to improve exercise ability and delay clinical worsening.
Pharmacology
High-affinity ETA receptor antagonist blocking vasoconstriction and cell proliferation mediated by Endothelin-1.
Dosage
Adult dose: Initial treatment is 5 mg once daily, can be increased to 10 mg once daily. Administered with or without food.
Side effects
Decreases in hemoglobin concentration, hematocrit, and peripheral edema.
Use in pregnancy
Pregnancy Category X. Contraindicated in pregnancy.
Pregnancy Category: X — always consult a doctor before taking during pregnancy.
Precautions & warnings
Monitor for fluid retention, pulmonary veno-occlusive disease, hematological changes; avoid in moderate/severe hepatic impairment.
Overdose effects
Supportive care as needed.
Storage conditions
Store below 30°C, protected from light and moisture.