৳ 22/unit
Pack: ৳ 220
৳ 22/unit
Pack: ৳ 220
At a glance
Domperidone + Esomeprazole is a combination medicine used for the treatment of gastroesophageal reflux disease (GERD), acid reflux, indigestion, nausea and vomiting. Domperidone helps the stomach empty faster and Esomeprazole reduces stomach acid production.
Indications
Gastroesophageal reflux disease (GERD), acid reflux, heartburn, indigestion (dyspepsia), flatulence, feeling of fullness after eating, nausea and vomiting.
Pharmacology
Domperidone is a dopamine antagonist with anti-emetic and gastrokinetic properties. It increases lower esophageal pressure, improves antroduodenal motility and accelerates gastric emptying. Esomeprazole suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase enzyme in the gastric parietal cell.
Dosage
Adults: Usually twice daily (morning and evening) or as prescribed by the physician. Available as capsules or tablets containing Domperidone 10-30mg and Esomeprazole 20-40mg. Should be taken 30 minutes before meals on an empty stomach.
Side effects
Common side effects: Headache, diarrhea, nausea, flatulence, abdominal pain, constipation, dry mouth. Rare side effects: Dizziness, drowsiness, allergic reactions.
Use in pregnancy
Use with caution during pregnancy. Animal studies have shown harmful effects on the fetus, but human studies are limited.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Caution during pregnancy. Not recommended during breastfeeding. Caution in elderly patients and those with cardiac problems or electrolyte abnormalities. Caution while driving as it may cause dizziness. Long-term use may increase fracture risk. Avoid alcohol.
Overdose effects
Symptoms of overdose: Drowsiness, irregular heartbeat, stomach discomfort. Seek medical attention immediately if overdose is suspected.
Storage conditions
Store below 30°C in a cool and dry place, protected from light. Keep out of reach of children.