৳ 20/unit
Pack: ৳ 20
৳ 20/unit
Pack: ৳ 20
At a glance
Tamsulosin + Dutasteride is a combination medicine used for moderate to severe symptoms of benign prostatic hyperplasia (BPH). It improves urine flow and reduces prostate size.
Indications
- Moderate to severe symptoms of Benign Prostatic Hyperplasia (BPH)
- Reduction in risk of acute urinary retention and surgery
Pharmacology
Tamsulosin blocks alpha-1 adrenoceptors in the prostate, prostatic capsule, urethra, and bladder neck, relaxing smooth muscle and improving urine flow. Dutasteride inhibits Type I and II 5-alpha reductase enzymes, preventing testosterone conversion to DHT, reducing prostate size and improving the static component of BPH.
Dosage
Adult Dose (Oral):
- 1 capsule (Tamsulosin 0.4 mg + Dutasteride 0.5 mg) once daily
- Take approximately 30 minutes after the same meal each day
- Swallow capsule whole; do not chew or open
Side effects
Common Side Effects:
- Impotence (erectile dysfunction)
- Decreased libido
- Breast pain and enlargement
- Ejaculation disorders
- Dizziness
Use in pregnancy
Use in Pregnancy: Highly unsafe; contraindicated in women; male patients with pregnant partners should use condoms; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Risk of cardiac failure (with dutasteride + alpha-blocker combination)
- PSA levels decrease by approximately 50%; establish new baseline after 6 months
- Intraoperative Floppy Iris Syndrome (IFIS) – discontinue before cataract surgery
- Do not use in severe hepatic impairment
- Contraindicated in women, children, and adolescents
Overdose effects
No overdose data available; tamsulosin overdose may cause acute hypotension, vomiting, diarrhea; dutasteride up to 40 mg/day is tolerated; provide symptomatic and supportive treatment.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.