oshudhkosh

Fastdol325mg+37.5mg

Rx
Dosage form:
Tablet
Pack size:
Strip (10 Tablet)

৳ 8/unit

Pack: ৳ 80

At a glance

Paracetamol + Tramadol Hydrochloride — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Paracetamol + Tramadol Hydrochloride is a pain relieving medicine. It is used in various conditions such as muscle ache, back pain, joint pain, menstrual cramps, and toothache. Paracetamol + Tramadol Hydrochloride can be taken with or without food. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it. Using this medicine may cause few common side effects such as nausea, vomiting, constipation, weakness, and dryness in mouth. If you experience any such side effects that do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms. Before using the medicine, you should tell your doctor if you have any other medical conditions or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. It should be used with caution in patients who are alcoholic or have liver or kidney disease. Pregnant and breastfeeding women should consult their doctors first before using the medicine. Paracetamol + Tramadol Hydrochloride is a combination of two medicines: Paracetamol/Acetaminophen and Tramadol. Paracetamol/Acetaminophen is an analgesic (pain reliever) which works by blocking the release of certain chemical messengers that cause pain. Tramadol is an opioid analgesic (pain reliever) which works by blocking the transmission of pain signals to the brain to lower pain perception.

Indications

• Pain relief

Mechanism of action

Tramadol is a centrally acting opioid analgesic which binds to mu-opioid receptors and weakly inhibits the reuptake of norepinephrine and serotonin. Paracetamol, a para-aminophenol derivative, has analgesic, antipyretic and weak anti-inflammatory activity. Together, tramadol and paracetamol has faster onset of action compared to tramadol alone and longer duration of action compared to paracetamol alone.

Dosage

Adult Dose: Oral Moderate to severe pain Adult: 1-2 tab 6 hrly. Max: 8 tab/day. Max duration: 5 days. Hepatic impairment: Moderate: Increase dosing interval. Severe: Contraindicated. Child Dose: Not recommended in child under 18 years of age. Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation 10-30 Increase dosing interva to 12 hr.ly <10 Not recommended.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Paracetamol + Tramadol Hydrochloride may be taken with or without food, but it is better to take it at a fixed time.

Side effects

Common: • Nausea • Vomiting • Constipation • Weakness • Dizziness • Dryness in mouth • Sleepiness

Precautions & warnings

[UNSAFE] Paracetamol + Tramadol Hydrochloride may cause side effects which could affect your ability to drive. Paracetamol + Tramadol Hydrochloride may cause side effects such as drowsiness and blurred vision. If this happens, do not drive. Use only for severe acute pain for not more than 5 days. Prolonged use may result in physical and psychological dependence even at recommended dosages. It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery. It is better to take with food to avoid an upset stomach. Your doctor may adjust your dose if you have liver or kidney disease. In case of overdose, tell your doctor immediately.

Contraindications

Hypersensitivity to tramadol, paracetamol or opioids. Situations where opioid use may be contra-indicated (e.g. acute intoxication with alcohol, hypnotic drugs, centrally-acting analgesics, opioids or psychotropic drugs). Severe hepatic impairment, uncontrolled epilepsy. Concurrent use or within 2 wk of discontinuation from MAOIs.

Drug interactions

Increased risk of seizures and serotonin syndrome w/ SSRIs, SNRIs, TCAs, and 5-HT agonists (e.g. sumatriptan). Increased CNS depression w/ barbiturates, benzodiazepines, other anxiolytics, hypnotics, sedative antidepressants, sedative antihistamines, neuroleptics, centrally-acting antihypertensive drugs, thalidomide and baclofen. Decreased analgesic efficacy w/ ondansetron. Increased INR w/ warfarin. Potentially Fatal: Increased risk of seizure and serotonin sydrome w/ MAOIs.

Food interactions

[UNSAFE] It is unsafe to consume alcohol with Paracetamol + Tramadol Hydrochloride.

Use in pregnancy

[CONSULT YOUR DOCTOR] Paracetamol + Tramadol Hydrochloride may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Paracetamol + Tramadol Hydrochloride is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.

Renal / hepatic impairment

[CAUTION] Paracetamol + Tramadol Hydrochloride should be used with caution in patients with kidney disease. Dose adjustment of Paracetamol + Tramadol Hydrochloride may be needed. Please consult your doctor. [CAUTION] Paracetamol + Tramadol Hydrochloride should be used with caution in patients with liver disease. Dose adjustment of Paracetamol + Tramadol Hydrochloride may be needed. Please consult your doctor.

Common questions

Plz dr. suggest me periods pain reliefer tablet which available easily at store. You can take govern tablets for pain relief Dear doctor my wife is 4 month pregnant since afternoon she is suffering from head ache , can you please suggest me what should be done Tablet Crocin pain relief can. E given I have piles problem for last 30 days and i just want to know which medicine or tablet i should take right now which can relief my pain and bleeding. Kindly suggest me tablet zerodol for pain relief Sits bath Consult a surgeon Avoid constipation Severe tooth pain and swelling what tablet can be used for emergency just for pain relief you can take ketorol dt 2 tabs dissolved in half glass of water. further you must consult a dentist for the right treatment. One of my teeth is sensitive. It some times pains sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief Pain in teeth age 15 male pain relief tablet Tab Dolo 650 1 SOS fever and 2 months pregnant can take combiflan No take Crocin for pain relief Suggest me medicine for quick releafe as m having back pain in right side. Take any pain killer for quich relief

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.