Flecard 50

• Supraventricular Arrhythmias: Used for irregular heart beat that starts in the upper chambers of the heart.
• Ventricular Arrhythmias: Used for irregular heart beat that starts in the lower chambers of the heart.
• Atrial Fibrillation: Used for rapid contractions of muscles in the heart.

Flecainide blocks fast inward sodium channels and slowly unbinds during diastole, prolonging the refractory period of the heart. This blockade also shortens the duration of action potentials through the Purkinjie fibers. Flecainide also prevents delayed rectifier potassium channels from opening, lengthening the action potential through ventricular and atrial muscle fibers.

Adult Dose (Oral):

• Supraventricular Arrhythmias: 50 mg twice a day; up to 300 mg daily.
• Ventricular Arrhythmias: 100 mg twice a day; up to 400 mg daily.
• Elderly and patients with kidney/heart problems: Lower dose may be required.

Child Dose: Not recommended for children under 12 years.

Common Side Effects (up to 1 in 10):

• Heartbeat changes (palpitations, faster or slower heartbeat)
• Chest pain
• Breathlessness
• Fever, flushing, sweating
• Fainting or feeling faint

Rare Side Effects (up to 1 in 1,000):

• Ringing in ears
• Jaundice (yellowing of skin and eyes)
• Seizures

Use in Pregnancy: Limited data on use during pregnancy; consult your doctor.

Precautions:

• Inform doctor if you have high blood pressure, angina, heart disease, kidney disease, or liver disease.
• Inform doctor if you wear a pacemaker.
• Your doctor may perform check-ups during treatment (fluid levels, liver and kidney function).

Overdose: Limited information on overdose; symptomatic treatment.

Storage: Keep below 30 degree C, away from light and moisture. Keep out of reach of children.