Flomyst-F 5/125125mcg+5mcg/Puff
Rx- Company:
- Beximco Pharmaceuticals Ltd.
- Dosage form:
- Inhaler
- Pack size:
- 120 Metered Doses
৳ 625/unit
Pack: ৳ 625
At a glance
Fluticasone propionate + Formoterol fumarate inhaler — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Fluticasone propionate + Formoterol fumarate inhaler is used in the treatment of asthma (wheezing and shortness of breath) and chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked). It relaxes the muscles of the air passages and making it easier to breathe. Your doctor will tell you how often you need to use your inhaler. It's important that you take the lowest dose needed to effectively control your asthma. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it's doing its job. If you stop taking it your asthma and COPD may get worse. It should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler (reliever). To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it Does not work as well. The most common side effects are nausea, vomiting, respiratory tract infection, fungal infections in the mouth, headache, hoarseness of voice, sore throat, cough, musculoskeletal (bone, muscle or joint) pain, and increased heart rate. If you get there, don't stop taking it but do talk to your doctor. You can help prevent some of these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other, rarer side effects which can be serious. Talk to your doctor if you're worried about them. In general, you should be trying to avoid situations that make your asthma worse (your triggers) and try not to smoke. Ask your doctor whether it's safe to take this medicine if you're pregnant or breastfeeding. Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Fluticasone propionate + Formoterol fumarate inhaler is a combination of two medicines: Formoterol and Fluticasone Propionate. Formoterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.
Indications
• Asthma • Chronic obstructive pulmonary disease (COPD)
Mechanism of action
Fluticasone propionate is a synthetic, trifluorinated glucocorticoid with potent anti-inflammatory activity in the lungs when given by inhalation. Fluticasone propionate reduces symptoms and exacerbations of asthma with less adverse effects than when corticosteroids are administered systemically. Formoterol fumarate is a long-acting selective β2 adrenergic receptor agonist. Inhaled formoterol fumarate acts locally in the lung as a bronchodilator. The onset of bronchodilating effect is rapid, within 1 - 3 minutes, and the duration of effect is at least 12 hours after a single dose.
Dosage
Adult Dose: Inhalation Per actuation Fluticasone + Formoterol: 50/5, 125/5 and 250/10 mcg Recommended dose for Adults 250/10 mcg Inhaler: 2 inhalations (puffs) twice daily. 50 /5 mcg inhaler - 2 inhalations (puffs) twice daily normally taken in the morning and in the evening. 125/5 mcg inhaler - 2 inhalations (puffs) twice daily normally taken in the morning and in the evening. Child Dose: Child < 12years not recommended. Recommended dose Adolescents aged 12 years and above: 50 /5 mcg inhaler - 2 inhalations (puffs) twice daily normally taken in the morning and in the evening. 125/5 mcg inhaler - 2 inhalations (puffs) twice daily normally taken in the morning and in the evening.
Administration
Check the label for directions before use. Shake the inhaler. While you are breathing in from mouth, press down on the inhaler one time to release the medication and hold your breath for 10 seconds. Repeat until you have inhaled the number of puffs as suggested by the doctor.Afterwards, rinse your mouth thoroughly with water and spit it out.
Side effects
Common: • Nausea • Vomiting • Respiratory tract infection • Fungal infection of mouth • Sore throat • Headache • Hoarseness of voice • Cough • Musculoskeletal (bone, muscle or joint) pain • Increased heart rate
Precautions & warnings
No interaction found/established Fluticasone propionate + Formoterol fumarate inhaler is a combination of two medicines that opens the airways and makes it easier to breathe. This medicine is for inhalation only. The tablet should not be swallowed. It should be taken at the same time each day. It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help. Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat. Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using. Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Fluticasone propionate + Formoterol fumarate inhaler can lower blood potassium level. Only miniscule amounts of Fluticasone propionate + Formoterol fumarate inhaler may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.
Contraindications
Hypersensitivity to the active substances or to any of the excipients. .
Drug interactions
Long-term treatment & co-administration w/ CYP3A4 inhibitors (eg, ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nelfinavir, saquinavir, ketoconazole, telithromycin). Non-K sparing diuretics (loop or thiazide diuretics), xanthine derivatives, glucocorticosteroids. L-dopa, L-thyroxine, oxytocin, alcohol can impair cardiac tolerance towards β2-sympathomimetics. Concomitant use w/ MAOIs, furazolidone & procarbazine may precipitate hypertensive reactions. Concomitant use w/ anaesth & halogenated hydrocarbons can elevate risk of arrhythmias. Additive effects w/ β-adrenergics. Increase risk of arrhythmias w/ digitalis glycosides. Administer w/ extreme caution to patients concomitantly taking TCAs or MAOIs & during the immediate 2 wk period following discontinuation. Increased risk of ventricular arrhythmias w/ phenothiazines, quinidine, disopyramide, procainamide & antihistamine. Potentiate sympathetic effect w/ adrenergic drugs. Inhibit the effect of β-blockers. Concomitant use w/ β-blockers including those used as eye drops or for glaucoma treatment.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Fluticasone propionate + Formoterol fumarate inhaler.
Use in pregnancy
[CONSULT YOUR DOCTOR] Fluticasone propionate + Formoterol fumarate inhaler may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Fluticasone propionate + Formoterol fumarate inhaler is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
No interaction found/established No interaction found/established
Common questions
i m suffering from breathing problem cough chest infame . Do tell chronic obstructive pulmonary disease .So tell which medicines should i take to treat this problem. It is less likely you have copd at this age You need detailed check up and spirometry test for same I have breathing problem.i was diagnosed with BRONCHITIC ASTHMA I want to know that which medicines are good for it. I have been using formoflo inhaler from lupin pharmacy.and i take it 2 puffs a day. consult chest physician for the same I had been made treatment for chest allergy before 3years and used formoflo 100, and odimont FX tablet for about 6 -8 months. After the problem solved I have discontinued the treatment. Now I have problem with my chest that there is cough. What to do sir. You may be having recurrent bronchitis/ asthma and may require inhalers again. Consult a doctor near you and get examined Old cough at morning last 15 years can be bronchial asthma or COPD consult chest physician What is chronic pulmonary thromboembolism? U can Google for details What is copd what is the best solution for it Copd is smokers disease. Read more about it at : http://www.arohealth.com/copd/ Chronic pulmonary obstacle. Suffering cough and breathing problem X ray has to be seen, and other blood reports too I have a problem of cold from my childhood and asthma Asthma needs assessment by pulmonary function tests and subsequent therapy depending on that