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At a glance

Devil's Claw (Harpagophytum procumbens) is a herbal preparation used for the treatment of low back pain and osteoarthritis.

Indications
  • Low back pain
  • Osteoarthritis (hip and knee)
Pharmacology

Devil's claw contains chemicals that might decrease inflammation and swelling and resulting pain.

Dosage

Osteoarthritis: Harpadol (Arkopharm) 2.6 g/day (57 mg harpagoside, 87 mg iridoid glycosides) OR Doloteffin (Ardeypharm) 2400 mg/day.
Back pain: Doloteffin (Ardeypharm) 50-100 mg harpagoside/day.

Side effects

Common: Diarrhea (in ~8% of people in one study), nausea, vomiting, abdominal pain, headaches, ringing in the ears, loss of appetite, loss of taste.
Other: Allergic skin reactions, menstrual problems, changes in blood pressure.

Use in pregnancy

Avoid use during pregnancy (may harm the developing fetus).

Pregnancy Category: N/A — always consult a doctor before taking during pregnancy.

Precautions & warnings

Caution in heart problems, high blood pressure, low blood pressure (may affect heart rate and blood pressure); diabetes (may lower blood sugar, dose adjustment of diabetes medications may be needed); avoid in gallstones (may increase bile production); avoid in peptic ulcer disease (may increase stomach acid production).

Overdose effects

No adequate information on overdose is available. If you take more than the recommended dose, consult your doctor.

Storage conditions

Keep below 30°C temperature, away from light & moisture. Keep out of reach of children.

Devil's Claw — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.