৳ 13.09/unit
Pack: ৳ 13.09
৳ 13.09/unit
Pack: ৳ 13.09
At a glance
Fluticasone Propionate Inhalation is a steroid used to relieve symptoms of allergic rhinitis such as runny nose, sneezing and sinus discomfort.
Indications
- Seasonal and perennial allergic rhinitis
- Asthma prophylaxis
Pharmacology
Fluticasone Propionate is a synthetic, trifluorinated corticosteroid that provides anti-inflammatory activity. It utilises a fluorocarbothioate ester linkage at the 17 carbon position. It has potent vasoconstrictive and anti-inflammatory activity, but weak HPA inhibitory effect when applied topically. Fluticasone has shown to exhibit anti-inflammatory effect on neutrophils, eosinophils, macrophages, mast cells, lymphocytes, and mediators (histamine, leukotrienes, cytokines, eicosanoids).
Dosage
Adult Dose (Asthma prophylaxis):
- Powder or aerosol inhaler: 100 mcg bid in mild asthma, up to 500-1,000 mcg bid in severe cases.
- Nebuliser suspension (16+ years): 0.5-2 mg twice daily. Initial dose: 2 mg twice daily.
Child Dose (4-16 years):
- 50-100 mcg bid, increased to 200 mcg bid if necessary.
- Under 4 years: Safety and efficacy not established.
- Nebuliser suspension (4-16 years): 1 mg twice daily.
* Use as directed by the registered physician
Side effects
Common Side Effects:
- Nasal irritation
- Nosebleeds
- Headache
Use in pregnancy
Use in Pregnancy: May be unsafe during pregnancy. Animal studies have shown harmful effects. Your doctor will weigh the benefits and risks.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Avoid in patients with recent nasal ulcers, nasal surgery, or nasal trauma.
- Do not use for primary treatment of status asthmaticus or acute bronchospasm.
- Long-term use may require regular medical tests.
Overdose effects
Overdose: Limited information available on overdose. Employ usual supportive measures.
Storage conditions
Storage: Store below 30°C, away from light and moisture. Keep out of reach of children.