৳ 20/unit
Pack: ৳ 200
৳ 20/unit
Pack: ৳ 200
At a glance
Tranexamic Acid is used to treat bleeding. It helps to prevent or reduce bleeding in conditions like tooth removal, heavy periods, dysfunctional uterine bleeding, nosebleed and in any oral, prostate or bladder surgery.
Indications
- Bleeding
- Heavy periods
- Dysfunctional uterine bleeding
- Nosebleed
- Tooth removal
- Prostate or bladder surgery
Pharmacology
Tranexamic acid inhibits plasminogen activation (streptokinase, urokinase, tissue plasminogen activator). It prevents breakdown of fibrin clots, thereby controlling bleeding. At therapeutic doses, it does not interfere with clotting processes.
Dosage
Adult Dose:
- Oral: 1-1.5 g or 15-25 mg/kg twice or three times daily
- IV: 0.5-1 g or 10 mg/kg three times daily or 25-50 mg/kg daily by continuous infusion
Child Dose:
- Oral: 25 mg/kg twice or three times daily
- IV: 10 mg/kg twice or three times daily
Renal impairment: Serum creatinine 120-250 micromol/l: 15 mg/kg twice daily; 250-500: 15 mg/kg once daily; >500: 7.5 mg/kg once daily
Side effects
Common Side Effects:
- Tiredness
- Nasal congestion
- Musculoskeletal pain
- Nausea
- Diarrhea
- Gastric pyrosis
Use in pregnancy
Use in Pregnancy: Generally considered safe; animal studies show low or no adverse effects; consult your doctor.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Does not usually affect ability to drive
- For heavy periods, take on the first day
- Use lowest effective dose for shortest possible time
- Inform doctor if history of kidney or liver disease
- Regular vision monitoring may be needed
Overdose effects
Symptoms: Headache, nausea, diarrhea, convulsions.
Treatment: Supportive care.
Storage conditions
Store in a dry place at 15-30°C, away from light; keep out of reach of children.