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At a glance

Aluminium Oxide + Magnesium Trisilicate is a combination antacid used to neutralize excess stomach acid and treat heartburn, indigestion, gastric hyperacidity, peptic ulcer, and GERD.

Indications

Heartburn, indigestion, gastric hyperacidity, peptic ulcer disease, gastroesophageal reflux disorder (GERD).

Pharmacology

Aluminium hydroxide neutralizes gastric HCl to form aluminium chloride salt and water, increasing gastric pH and reducing acidity. Magnesium trisilicate neutralizes gastric acidity by increasing gastric pH. The combined action of these two components provides rapid relief from heartburn and indigestion.

Dosage

Suspension: Take 2-4 teaspoonfuls (10-20 mL) after meals and at bedtime as needed (up to 4 times a day).

Side effects

Common side effects: Diarrhea, constipation, nausea, vomiting.

With long-term use: Alkaluria (may predispose to nephrolithiasis by forming calcium phosphate precipitation), hypophosphataemia.

Serious (rare): Aluminium intoxication (in chronic renal failure), hypermagnesaemia (in renal disease).

Use in pregnancy

There is limited information on the use of aluminium oxide + magnesium trisilicate during pregnancy. It is advised to avoid antacids in the first trimester of pregnancy.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution in chronic renal impairment (risk of aluminium accumulation)
  • Caution in low phosphate diets
  • Avoid long-term use
  • Maintain 2 hour gap with other medications (to avoid absorption interference)
  • Avoid use in the first trimester of pregnancy
  • Caution during lactation
Overdose effects

Overdose symptoms: severe constipation, intestinal obstruction, diarrhea, electrolyte imbalance. Treatment: drug discontinuation and symptomatic measures.

Storage conditions

Store below 30°C, protected from light and moisture. Keep out of reach of children.

Aluminium Oxide + Magnesium Trisilicate — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.