G Methyl Ergometrine
125mcgRx৳ 0.60/unit
Pack: ৳ 0.60
৳ 0.60/unit
Pack: ৳ 0.60
At a glance
Methyl Ergometrine Maleate is a medicine used to control bleeding from the uterus that may occur after childbirth or abortion.
Indications
- Post-delivery bleeding (Postpartum Hemorrhage)
- Active management of the third stage of labor
- Post-abortion bleeding
- Excessive uterine bleeding
Pharmacology
Methyl Ergometrine Maleate causes contraction of the uterine muscle. At low doses, there is an increase in frequency and amplitude of contractions while at higher doses, the basal tone of the uterus is increased. It also causes peripheral and cerebral vasoconstriction.
Dosage
Adult Dose:
- Oral: Prophylaxis of postpartum hemorrhage: 200 mcg, 3-4 times daily for 2-7 days.
- Intramuscular (IM): Treatment and prophylaxis of postpartum and postabortal hemorrhage: 200 mcg. May repeat every 2-4 hours as needed. Max: 5 doses.
- Intravenous (IV): As an emergency measure: 200 mcg by slow injection over at least 1 minute. May repeat every 2-4 hours, up to a max of 5 doses.
Side effects
Common Side Effects:
- High blood pressure
- Headache
- Nausea, vomiting
- Abdominal pain, diarrhea
- Dizziness
- Chest pain, palpitation
- Seizures
Use in pregnancy
Use in Pregnancy (Category X): Highly unsafe. Contraindicated in women who are or may become pregnant. Risk of severe fetal harm.
Pregnancy Category: X — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution while driving, as the drug may affect concentration and reaction ability.
- Avoid in patients with high blood pressure, heart disease, eclampsia, or pre-eclampsia.
- Use with caution in patients with liver, kidney, or respiratory problems.
Overdose effects
Overdose may cause peripheral vasoconstriction, encephalopathy, convulsions, respiratory failure, acute renal failure, and temporary lactose intolerance. Treatment is supportive.
Storage conditions
Injection: Store in a refrigerator at 2-8°C. Tablet: Store below 25°C.