oshudhkosh

Glucon5mg

Rx
Dosage form:
Tablet
Pack size:
Tablet

৳ 0.34/unit

Pack: ৳ 0.34

At a glance

Glibenclamide — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Glibenclamide is a medicine used to treat type 2 diabetes mellitus in adults. It belongs to a group of medicines called sulfonylureas and helps control blood sugar levels in people with diabetes. This helps to prevent serious complications of diabetes like kidney damage and blindness. Glibenclamide may be used by itself or along with other medicines. It should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working. Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes. The most common side effects of taking this medicine include nausea, headache, and dizziness. It can also sometimes cause low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Some people may find that they put on weight with this medicine. You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease or some hormonal conditions. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function. Glibenclamide is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

Indications

• Type 2 diabetes mellitus

Mechanism of action

Glibenclamide lowers blood glucose concentration principally by stimulating secretion of endogenous insulin from the pancreatic beta-cells. Hypoglycaemic action associated w/ short-term therapy appears to include reduction of basal hepatic glucose production and enhancement of peripheral insulin action at target sites.

Dosage

Adult Dose: Oral Type 2 diabetes mellitus Adult: Initially, 2.5-5 mg daily, may increase wkly by increments of 2.5-15 mg daily. Doses >10 mg daily should be given in 2 divided doses. Max: 20 mg daily. Elderly: Initially, 1.25 mg daily. Hepatic impairment: Severe: Contraindicated. Child Dose: Safety and efficacy not established Renal Dose: Renal impairment: Severe: Contraindicated.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glibenclamide is to be taken with food.

Missed dose

You should skip a dose of Glibenclamide if a meal is skipped, and add a dose of medicine if you eat an extra meal.

Side effects

Common: • Hypoglycemia (low blood glucose level) • Nausea • Headache • Dizziness

Precautions & warnings

[CAUTION] Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur. Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals. Be careful while driving or operating machinery until you know how Glibenclamide affects you. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Contraindications

Severe or life-threatening hyperglycaemia, severe liver or renal failure, type 1 diabetes, diabetic ketoacidosis with or without coma, patients with severe infection or trauma.

Drug interactions

Serum levels may be reduced by colesevelam. May increase hypoglycaemic effect w/ MAOIs, chloramphenicol, fluoroquinolones (e.g. ciprofloxacin), probenecid, NSAIDs, ACE inhibitors, fluoxetine, disopyramide, clarithromycin, salicylates, sulfonamides, beta-blockers. Increased serum levels w/ antifungal antibiotics (e.g. miconazole, fluconazole). May decrease hypoglycaemic effect w/ nonthiazide (e.g. furosemide) and thiazide diuretics, corticosteroids, phenothiazines, thyroid agents, oestrogens, OC, phenytoin, nicotinic acid, sympathomimetic agents, rifampicin, Ca channel blockers, isoniazid. Potentially Fatal: May increase hepatotoxic effect of bosentan.

Food interactions

[UNSAFE] It is unsafe to consume alcohol with Glibenclamide.

Use in pregnancy

[SAFE IF PRESCRIBED] Glibenclamide is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Use in lactation

[SAFE IF PRESCRIBED] Glibenclamide is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Monitor the breastfed baby’s blood sugar during treatment with Glibenclamide

Renal / hepatic impairment

[UNSAFE] Glibenclamide is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor. [CAUTION] Glibenclamide should be used with caution in patients with liver disease. Dose adjustment of Glibenclamide may be needed. Please consult your doctor. Use of Glibenclamide is not recommended in patients with severe liver disease. They can experience very low blood sugar levels while taking this medicine.

Common questions

Diabetes mellitus type 2 ,thirst A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET Diabetes mellitus type 2 required only ayurvedic medicine Go for allopathic medicine Can i go for medicine daonil ?? A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED. ALWAYS IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you SHOULD not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at Gurugram, shiv puri mor Old railway Road, near Haris Bakery, PNL HEALTH CARE CLINIC (Advanced diabetic clinic) Can I take Daonil along with vitamin B complex? Is it a safe medicine of diabetes? Can take. It is safe I am taking obimet 500sr & Daonil 1-0-1 Fasting sugar 126 After food 3000 Sir you need proper care and investigations then only medicine can be prescribed . Plz consult doctor nearby or visit diabetic clinic in gurgaon sector 52 RDCITY baljeet shopping complex near SRS MARKET .SNERGY MULTI SPECIALITY CLINIC Care during type 2 diabetes mellitus?an manegment of life style. Hi Kindly once consult to Dietitian for proper diet chart Type || diabetes mellitus ischemic heart disease What did your tell u Any latest discoveris for type 1 mellitus Diabetes? Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.